NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	NQZ80_RS03600	Genome accession	NZ_CP102244
Coordinates	750290..750949 (-)	Length	219 a.a.
NCBI ID	WP_024216571.1	Uniprot ID	-
Organism	Escherichia coli O7:H15 strain ST70
Function	repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 745290..755949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ80_RS03575 (NQZ80_03575)	-	746032..746979 (+)	948	WP_001305988.1	iron-siderophore ABC transporter substrate-binding protein	-
NQZ80_RS03580 (NQZ80_03580)	-	746976..747863 (+)	888	WP_000614954.1	MurR/RpiR family transcriptional regulator	-
NQZ80_RS03585 (NQZ80_03585)	ygiN	747908..748222 (-)	315	WP_000633738.1	putative quinol monooxygenase	-
NQZ80_RS03590 (NQZ80_03590)	mdaB	748253..748834 (-)	582	WP_001392669.1	NADPH:quinone oxidoreductase MdaB	-
NQZ80_RS03595 (NQZ80_03595)	qseC	748944..750293 (-)	1350	WP_024216572.1	quorum sensing histidine kinase QseC	-
NQZ80_RS03600 (NQZ80_03600)	ciaR	750290..750949 (-)	660	WP_024216571.1	quorum sensing response regulator transcription factor QseB	Regulator
NQZ80_RS03605 (NQZ80_03605)	ygiW	751101..751493 (+)	393	WP_000712658.1	OB fold stress tolerance protein YgiW	-
NQZ80_RS03610 (NQZ80_03610)	ygiV	751546..752028 (+)	483	WP_000183504.1	GyrI-like domain-containing protein	-
NQZ80_RS03615 (NQZ80_03615)	parC	752574..754832 (+)	2259	WP_001281890.1	DNA topoisomerase IV subunit A	-
NQZ80_RS03620 (NQZ80_03620)	plsC	755066..755803 (+)	738	WP_000965712.1	1-acylglycerol-3-phosphate O-acyltransferase	-

Sequence

Protein

Download Length: 219 a.a. Molecular weight: 24701.65 Da Isoelectric Point: 6.9850

                                >NTDB_id=615938 NQZ80_RS03600 WP_024216571.1 750290..750949(-) (ciaR) [Escherichia coli O7:H15 strain ST70]

MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPILILTA

RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL

LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide

Download Length: 660 bp

                                >NTDB_id=615938 NQZ80_RS03600 WP_024216571.1 750290..750949(-) (ciaR) [Escherichia coli O7:H15 strain ST70]

ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGTGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT

CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT

TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGATACTGATCCTGACCGCG

CGCGATGCGTTAGCGGAACGTGTAGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA

AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC

TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGTGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA

CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG

TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT

ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus pneumoniae TIGR4	37.885	100	0.393
ciaR	Streptococcus pneumoniae D39	37.885	100	0.393
ciaR	Streptococcus pneumoniae R6	37.885	100	0.393
ciaR	Streptococcus pneumoniae Rx1	37.885	100	0.393
covR	Lactococcus lactis subsp. lactis strain DGCC12653	34.956	100	0.361
micA	Streptococcus pneumoniae Cp1015	34.498	100	0.361
ciaR	Streptococcus mutans UA159	35.426	100	0.361

Detailed information NTG0615938