Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SII_RS06865 Genome accession   NC_022237
Coordinates   1415201..1415950 (-) Length   249 a.a.
NCBI ID   WP_020999014.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1410201..1420950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS06845 (SII_1347) - 1410626..1411858 (-) 1233 WP_020999010.1 cysteine desulfurase -
  SII_RS06850 (SII_1348) sufD 1411875..1413137 (-) 1263 WP_020999011.1 Fe-S cluster assembly protein SufD -
  SII_RS06855 (SII_1349) sufC 1413177..1413947 (-) 771 WP_041823272.1 Fe-S cluster assembly ATPase SufC -
  SII_RS06860 (SII_1350) - 1414038..1415204 (-) 1167 WP_041823275.1 glycosyltransferase family 4 protein -
  SII_RS06865 (SII_1351) mecA 1415201..1415950 (-) 750 WP_020999014.1 adaptor protein MecA Regulator
  SII_RS06870 (SII_1352) - 1416077..1416919 (-) 843 WP_003073751.1 undecaprenyl-diphosphate phosphatase -
  SII_RS06875 (SII_1353) - 1416986..1418875 (-) 1890 WP_020999015.1 DUF2207 domain-containing protein -
  SII_RS06880 (SII_1354) - 1419002..1420567 (+) 1566 WP_020999016.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 28996.74 Da        Isoelectric Point: 4.1860

>NTDB_id=61539 SII_RS06865 WP_020999014.1 1415201..1415950(-) (mecA) [Streptococcus intermedius C270]
MEMKQISDTTIKITIKLEDLEERGMEMTDFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDIEAVRSLETAEAENSRSTSDMEEQEEDNDELTQKYIYYI
LKFANLREVIVFAKTVDYTVNTSELYKMDSHYYLTILVDIEGHPKRYPAWLLASMREHAEDTAVTRAVLQEHGYLLLVND
AVSNLQKVK

Nucleotide


Download         Length: 750 bp        

>NTDB_id=61539 SII_RS06865 WP_020999014.1 1415201..1415950(-) (mecA) [Streptococcus intermedius C270]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GACAGATTTTCTCGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACCCCTAAACCAGACCGACTGGATGTTTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAATTTTGATGATTTAGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGCAAAGACGATATTGAAGCTGTTCGGTCTTTGGAAACGGCAGAAGCAG
AAAATAGTAGAAGCACTTCTGATATGGAAGAACAAGAGGAAGATAATGACGAGCTAACACAAAAATATATATATTACATT
TTGAAGTTTGCCAACCTAAGAGAAGTGATTGTTTTTGCTAAAACGGTAGATTATACCGTCAATACTTCAGAGTTATACAA
AATGGACAGTCACTATTATTTGACAATTTTGGTTGATATTGAAGGCCACCCTAAGCGATATCCGGCTTGGCTTCTTGCGT
CTATGCGTGAACATGCAGAAGATACAGCTGTGACAAGAGCTGTTTTGCAAGAGCATGGTTACTTATTGCTTGTCAACGAT
GCGGTTTCCAATCTTCAAAAGGTTAAATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

67.742

99.598

0.675
  mecA Streptococcus pneumoniae D39

67.742

99.598

0.675
  mecA Streptococcus pneumoniae R6

67.742

99.598

0.675
  mecA Streptococcus pneumoniae TIGR4

67.339

99.598

0.671
  mecA Streptococcus mutans UA159

51.613

99.598

0.514
  mecA Streptococcus thermophilus LMD-9

45.703

100

0.47
  mecA Streptococcus thermophilus LMG 18311

45.312

100

0.466

Multiple sequence alignment