Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SII_RS06695 Genome accession   NC_022237
Coordinates   1377839..1379713 (-) Length   624 a.a.
NCBI ID   WP_003073669.1    Uniprot ID   A0A3R9JBZ9
Organism   Streptococcus intermedius C270     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1372839..1384713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS06665 (SII_1312) - 1372981..1373298 (+) 318 WP_003073656.1 DUF960 domain-containing protein -
  SII_RS06670 (SII_1313) - 1373418..1373810 (-) 393 WP_003073658.1 S1 RNA-binding domain-containing protein -
  SII_RS06675 (SII_1314) - 1373812..1375212 (-) 1401 WP_003073660.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SII_RS06680 (SII_1315) - 1375252..1375884 (-) 633 WP_003073662.1 response regulator transcription factor -
  SII_RS06685 (SII_1316) - 1375886..1376881 (-) 996 WP_003073664.1 sensor histidine kinase -
  SII_RS06690 (SII_1317) liaF 1376878..1377576 (-) 699 WP_020998987.1 cell wall-active antibiotics response protein LiaF -
  SII_RS06695 (SII_1318) stkP 1377839..1379713 (-) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SII_RS06700 (SII_1319) - 1379710..1380450 (-) 741 WP_020998988.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SII_RS06705 (SII_1320) rsmB 1380469..1381782 (-) 1314 WP_020998989.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SII_RS06710 (SII_1321) fmt 1381772..1382707 (-) 936 WP_020998990.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67672.81 Da        Isoelectric Point: 9.6670

>NTDB_id=61537 SII_RS06695 WP_003073669.1 1377839..1379713(-) (stkP) [Streptococcus intermedius C270]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTVKADTKTLPKVSQNTLTSASKPTATSTKEAVD
NQTKPKPKPKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSDSAK
KDSVIRTNPQAGTQRREGSTVDLIVSKGPKTFTMEDYSGQKKADAINSLVQKYKVSKGLIKIEEVESSDYAAGTVVSQTP
AAGSTYDLTSKNRITLKVAKTVSSVTMPSYIGSTYEFAYNNLTEVIGVQGANVEKRIVTTAPAGTQAHTIIKQSPEAKRP
LNLKNDRIVLYVYEPKTEESSTSESSSQSGSSSNKNSPSSSSSSSSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=61537 SII_RS06695 WP_003073669.1 1377839..1379713(-) (stkP) [Streptococcus intermedius C270]
ATGATTCAAGTCGGCAAAATATTTGCCGGACGATATAGAATCATCAAACAAATCGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCGAAAGATTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAACTACCAGACAGATCCGATTG
CTGTAGCGCGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACTGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACCCAGACAAATTCAATGCTGGGATCTGTACATTATCTATCACCAGAACAGGCACGTGGGTC
AAAAGCAACAGTTCAAAGTGATATTTATGCTATGGGGATTATTTTCTATGAAATGCTGACAGGTCACATTCCTTATGATG
GGGATAGTGCTGTGACGATTGCACTGCAGCATTTCCAAAAACCCCTTCCTTCTGTAATTGCTGAAAATCCAAATGTTCCA
CAAGCATTAGAAAATGTGGTTATCAAGGCAACGGCAAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
TGACTTATCTAGTTGTTTATCTGCTGATCGTCGAAATGAGAAGAAATTAGTTTTTGATGATACTGTTAAAGCAGACACTA
AGACGCTTCCTAAAGTATCACAGAATACGTTGACTTCAGCGTCTAAACCGACTGCTACATCTACAAAAGAAGCTGTTGAT
AATCAAACTAAGCCTAAACCAAAACCAAAGAAAAAACGTCGCTTAAGAACACGTTATAAAGTGTTGTTGTCGGCAGTAGT
CTTAGTTATTGCAGCTTTGGTGGCTTTAGTCTATTTGAGTCCCTCAAATGTAAAAATACCAGATGTTACTGGAAAAACCG
TTGCGCAAGCACGTTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAGAAAGACGAATACAGTGATTCTGCTAAG
AAAGATTCTGTCATTCGTACGAATCCACAAGCGGGAACACAACGTCGCGAAGGAAGCACAGTAGATTTGATTGTCTCAAA
AGGGCCGAAAACATTTACTATGGAAGATTATAGCGGTCAGAAAAAAGCAGATGCTATCAACAGTTTGGTGCAAAAATACA
AAGTTTCAAAGGGCTTGATTAAAATTGAAGAAGTTGAAAGTAGTGATTATGCAGCAGGGACTGTTGTTAGTCAGACGCCA
GCAGCAGGTAGTACGTATGATTTGACTTCAAAAAATCGGATTACGTTAAAAGTAGCGAAGACGGTTTCAAGTGTTACAAT
GCCAAGTTATATAGGTTCCACTTATGAATTTGCCTATAATAACCTTACCGAAGTTATTGGCGTTCAAGGAGCTAATGTTG
AAAAACGAATAGTTACAACAGCTCCAGCAGGAACACAGGCACACACGATTATTAAACAAAGCCCAGAAGCAAAGAGGCCT
CTAAATCTAAAAAATGATCGTATTGTCTTATATGTATATGAGCCAAAAACTGAAGAATCATCCACATCTGAAAGTAGTTC
GCAATCTGGAAGCAGTTCAAATAAAAATAGTCCATCATCTAGTAGTTCGTCGAGTAGCGGTAACGATGGATCAAGTTCGA
AAACACCAGACACAAGCGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(433-500)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(364-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9JBZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.381

93.429

0.62
  stkP Streptococcus pneumoniae D39

66.038

93.429

0.617
  stkP Streptococcus pneumoniae R6

66.038

93.429

0.617
  stkP Streptococcus pneumoniae Rx1

65.866

93.429

0.615
  pknB Streptococcus mutans UA159

59.658

93.75

0.559
  stkP/pknB Streptococcus salivarius strain HSISS4

59.294

86.218

0.511

Multiple sequence alignment