Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LIO33_RS09600 Genome accession   NZ_CP085088
Coordinates   1963223..1964419 (+) Length   398 a.a.
NCBI ID   WP_012028059.1    Uniprot ID   D5AF49
Organism   Streptococcus suis strain Ssuis_MA1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1958223..1969419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO33_RS09570 - 1958882..1961461 (+) 2580 WP_012028056.1 YfhO family protein -
  LIO33_RS09590 - 1961862..1962545 (-) 684 WP_012775416.1 YoaK family protein -
  LIO33_RS09595 rlmH 1962570..1963049 (-) 480 WP_012028058.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LIO33_RS09600 htrA 1963223..1964419 (+) 1197 WP_012028059.1 S1C family serine protease Regulator
  LIO33_RS09605 spo0J 1964480..1965244 (+) 765 WP_012775418.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41866.92 Da        Isoelectric Point: 4.6543

>NTDB_id=615345 LIO33_RS09600 WP_012028059.1 1963223..1964419(+) (htrA) [Streptococcus suis strain Ssuis_MA1]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=615345 LIO33_RS09600 WP_012028059.1 1963223..1964419(+) (htrA) [Streptococcus suis strain Ssuis_MA1]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTGTCAGCCTCTTTCTTCCAGCCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAATATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(103-248)

PDZ domain (PDZ_2)

(293-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5AF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.194

99.749

0.59
  htrA Streptococcus gordonii str. Challis substr. CH1

58.987

99.246

0.585
  htrA Streptococcus pneumoniae D39

57.252

98.744

0.565
  htrA Streptococcus pneumoniae TIGR4

57.252

98.744

0.565
  htrA Streptococcus mitis NCTC 12261

57.252

98.744

0.565
  htrA Streptococcus pneumoniae R6

57.252

98.744

0.565
  htrA Streptococcus pneumoniae Rx1

57.252

98.744

0.565