Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SII_RS03735 Genome accession   NC_022237
Coordinates   739389..741623 (+) Length   744 a.a.
NCBI ID   WP_020998591.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 734389..746623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS09710 (SII_0728) rpmG 735251..735400 (+) 150 WP_003034401.1 50S ribosomal protein L33 -
  SII_RS03715 (SII_0729) secG 735440..735673 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  SII_RS03720 (SII_0730) rnr 735764..738103 (+) 2340 WP_020998588.1 ribonuclease R -
  SII_RS03725 (SII_0731) smpB 738066..738533 (+) 468 WP_020998589.1 SsrA-binding protein SmpB -
  SII_RS03730 (SII_0732) comEA/celA/cilE 738701..739405 (+) 705 WP_020998590.1 helix-hairpin-helix domain-containing protein Machinery gene
  SII_RS03735 (SII_0733) comEC/celB 739389..741623 (+) 2235 WP_020998591.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SII_RS03740 (SII_0734) - 741701..742411 (+) 711 WP_020998592.1 DUF805 domain-containing protein -
  SII_RS03745 (SII_0735) - 742852..743838 (+) 987 WP_020998593.1 Gfo/Idh/MocA family protein -
  SII_RS03750 (SII_0736) - 743867..744520 (+) 654 WP_009568677.1 uracil-DNA glycosylase -
  SII_RS03755 (SII_0737) - 744547..745017 (+) 471 WP_020998594.1 NUDIX hydrolase -
  SII_RS03760 (SII_0738) - 745029..746303 (+) 1275 WP_020998595.1 dihydroorotase -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85242.22 Da        Isoelectric Point: 10.2429

>NTDB_id=61518 SII_RS03735 WP_020998591.1 739389..741623(+) (comEC/celB) [Streptococcus intermedius C270]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSNWLAGVGSIFLLIRLSRIYSLKEWFTTFMILACFAVFFLVRRELADRKIKV
EAPPVRQVAVLPDTIKVNGDSLSFRGKAKGQTYQIYYKLKSKKEKLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSFQPFERLSSWRRKALVFIKRNFPNPMSNYMTGILFGALDTDFGEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKSLLRLGLTQEIVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLI
MPSFLLTAGGVLSCAYAFIISVLDFKGLTPYKKIIIESIVISLGILPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
IIFLVSPFIKLTQVNFLFECLESSIRWLASMFSRPVVLGKPNPLLLIAMLLVLAILYDIRQNKKWLIFLSLFLSLLFFVA
KFPLQNEITMIDVGKGDSIFMRDWRGSTVLIDVGGREEIRKKESWQERISSSNAERTLIPYLKSRGVDTIDTLVLTNPNS
DYAGDVLEVAKKFSIKKIFISRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKSDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGSQNSSSSKFLQQVRPVIALISTGKNNSSKSLSQETIERFNRLNTKIY
RTDKQGAIKFSGWTTWQLETVQQP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=61518 SII_RS03735 WP_020998591.1 739389..741623(+) (comEC/celB) [Streptococcus intermedius C270]
ATGTCACAGTGGATTAAGATATTTCCGATCAAACCAATTTACATTGCTTTCTTACTTGTCTGGTTATATTTTGCAATCTA
TCAAAGTAATTGGTTGGCAGGAGTGGGATCGATCTTTCTGTTAATTCGTCTTTCTCGCATATATTCGCTAAAAGAATGGT
TTACAACTTTCATGATTCTCGCTTGTTTTGCTGTTTTTTTCCTTGTTCGTAGGGAACTGGCGGATCGGAAGATAAAAGTA
GAAGCTCCTCCTGTAAGACAAGTTGCGGTTTTACCTGATACAATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCAAAAGGACAGACATATCAAATTTACTACAAATTGAAATCAAAAAAAGAAAAGTTGGCTTTTCAAAATCTATCCAGCC
TTGTTACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGCCAAGATAGGGTTAGCTTCCAACCGTT
TGAGCGGCTGTCTAGCTGGCGAAGAAAAGCATTGGTTTTCATTAAGAGAAATTTCCCGAATCCAATGAGCAATTATATGA
CAGGGATTTTGTTCGGAGCTTTGGATACAGATTTTGGTGAAATGAATAACCTTTATTCGAGCTTGGGAATTATTCATTTA
TTTGCATTGTCTGGTATGCAAGTTGGTTTTTTTATGGAAGGGTTTCGTAAGTCACTGTTGAGATTGGGGCTTACGCAGGA
AATAGTTCATAAGTGTCAATATCCATTTTCTTTTTTTTATGCTGGAATGACAGGTTTTTCAGTATCCGTTGTACGGAGTT
TAATCCAGAAATTATTGTCACAACACGGCATTACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGATT
ATGCCCTCCTTTCTTTTAACAGCAGGAGGAGTACTTTCTTGTGCGTATGCTTTTATCATTAGCGTTTTAGATTTTAAAGG
CCTGACTCCTTATAAAAAGATTATTATAGAGAGTATTGTCATTTCGCTTGGCATTTTACCAATTTTAATCTTTTATTTCG
GAGAATTTCAGCCCTGGTCTATTTTATTGACATTTGTTTTTTCGTTGATTTTCGATATAGTGATGTTACCGGGGCTAACG
ATAATTTTTCTTGTTTCCCCTTTCATAAAACTCACTCAAGTTAATTTTCTATTTGAATGCTTAGAAAGTAGCATTCGCTG
GTTAGCAAGTATGTTTAGCAGACCAGTCGTTCTTGGCAAACCTAATCCACTTTTGCTAATCGCTATGTTGCTTGTATTAG
CTATCTTGTATGATATTCGGCAAAATAAAAAATGGCTGATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTTGTAGCT
AAATTTCCTTTACAAAATGAAATCACAATGATTGATGTCGGGAAGGGAGATAGTATTTTTATGCGAGACTGGAGAGGGAG
CACTGTATTGATTGATGTTGGCGGACGTGAAGAAATTAGAAAAAAAGAAAGTTGGCAAGAACGTATAAGTAGTTCAAACG
CAGAGAGAACGCTGATTCCATATCTTAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCAAATTCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAGTTTTCGATAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGGGCGTTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAGTGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAACTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGATCCCAAAATTCATCAAGTTCTAAGTTCTTACAGCAAGTAAGACCAGTGATTGCCCTCATCT
CTACTGGGAAAAACAATTCATCCAAATCGCTAAGTCAAGAAACAATTGAGCGATTCAATCGGTTAAATACAAAGATCTAT
CGAACAGATAAACAGGGGGCTATTAAGTTTTCGGGTTGGACAACATGGCAATTAGAAACTGTTCAGCAACCATAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(217-461)

Domain of unknown function (DUF4131) (DUF4131)

(31-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

55.556

100

0.558
  comEC/celB Streptococcus mitis NCTC 12261

55.362

100

0.555
  comEC/celB Streptococcus pneumoniae TIGR4

54.351

100

0.546
  comEC/celB Streptococcus pneumoniae Rx1

53.815

100

0.54
  comEC/celB Streptococcus pneumoniae D39

53.815

100

0.54
  comEC/celB Streptococcus pneumoniae R6

53.815

100

0.54
  comEC Lactococcus lactis subsp. cremoris KW2

46.371

100

0.464

Multiple sequence alignment