Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SCRE_RS08600 Genome accession   NC_022236
Coordinates   1733090..1734031 (-) Length   313 a.a.
NCBI ID   WP_006268058.1    Uniprot ID   F9P809
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1728090..1739031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS08560 (SCRE_1681) - 1728147..1729346 (-) 1200 WP_006267970.1 acetate kinase -
  SCRE_RS08565 (SCRE_1682) comYH 1729393..1730346 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  SCRE_RS08570 (SCRE_1683) comGG 1730431..1730757 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  SCRE_RS08575 (SCRE_1684) comGF/cglF 1730738..1731175 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCRE_RS08580 (SCRE_1685) comGE/cglE 1731159..1731452 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCRE_RS08585 (SCRE_1686) comYD 1731424..1731852 (-) 429 WP_020998067.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCRE_RS08590 (SCRE_1687) comYC 1731812..1732129 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SCRE_RS08595 (SCRE_1688) comYB 1732126..1733148 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCRE_RS08600 (SCRE_1689) comYA 1733090..1734031 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  SCRE_RS08605 - 1734101..1734466 (-) 366 WP_022525692.1 DUF1033 family protein -
  SCRE_RS08610 (SCRE_1690) glnA 1734654..1736000 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  SCRE_RS08615 (SCRE_1691) - 1736039..1736398 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  SCRE_RS08620 (SCRE_1692) - 1736475..1737005 (-) 531 WP_006268314.1 FUSC family protein -
  SCRE_RS08625 - 1737144..1737428 (-) 285 WP_006268247.1 2'-5' RNA ligase family protein -
  SCRE_RS08630 - 1737431..1737637 (-) 207 WP_006268044.1 hypothetical protein -
  SCRE_RS08635 (SCRE_1693) - 1737703..1738899 (-) 1197 WP_006268026.1 phosphoglycerate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35973.15 Da        Isoelectric Point: 6.3145

>NTDB_id=61495 SCRE_RS08600 WP_006268058.1 1733090..1734031(-) (comYA) [Streptococcus constellatus subsp. pharyngis C232]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFANQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=61495 SCRE_RS08600 WP_006268058.1 1733090..1734031(-) (comYA) [Streptococcus constellatus subsp. pharyngis C232]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTTAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACGTCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCAATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P809

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

76.038

100

0.76
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.719

100

0.757
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.478

88.179

0.383

Multiple sequence alignment