Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NP436_RS21655 Genome accession   NZ_CP101932
Coordinates   4057359..4058561 (-) Length   400 a.a.
NCBI ID   WP_014481472.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. natto strain BGSC 27E1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4052359..4063561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP436_RS21620 (NP436_21620) - 4052837..4053790 (-) 954 WP_014481469.1 sporulation-delaying protein SdpB family protein -
  NP436_RS21625 (NP436_21625) - 4053775..4054329 (-) 555 WP_015715050.1 SdpA family antimicrobial peptide system protein -
  NP436_RS21630 (NP436_21630) - 4054513..4055148 (-) 636 WP_014481470.1 SdpI family protein -
  NP436_RS21635 (NP436_21635) - 4055148..4055432 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  NP436_RS21640 (NP436_21640) rocR 4055659..4057044 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  NP436_RS21645 (NP436_21645) - 4057026..4057178 (-) 153 Protein_4210 ATP-binding protein -
  NP436_RS21650 (NP436_21650) - 4057206..4057338 (-) 133 Protein_4211 hypothetical protein -
  NP436_RS21655 (NP436_21655) htrA 4057359..4058561 (-) 1203 WP_014481472.1 serine protease HtrC Regulator
  NP436_RS21660 (NP436_21660) vicX 4058643..4059437 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  NP436_RS21665 (NP436_21665) walI 4059459..4060301 (-) 843 WP_014481473.1 WalRK two-component regulatory system regulator WalI -
  NP436_RS21670 (NP436_21670) walH 4060288..4061655 (-) 1368 WP_014481474.1 WalRK two-component regulatory system regulator WalH -
  NP436_RS21675 (NP436_21675) walK 4061645..4063480 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42761.51 Da        Isoelectric Point: 5.1904

>NTDB_id=613257 NP436_RS21655 WP_014481472.1 4057359..4058561(-) (htrA) [Bacillus subtilis subsp. natto strain BGSC 27E1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGVVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=613257 NP436_RS21655 WP_014481472.1 4057359..4058561(-) (htrA) [Bacillus subtilis subsp. natto strain BGSC 27E1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAATGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCAGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(231-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375