NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	NP447_RS02195	Genome accession	NZ_CP101920
Coordinates	456882..458006 (+)	Length	374 a.a.
NCBI ID	WP_001402665.1	Uniprot ID	-
Organism	Escherichia coli strain QA-1986 630
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 451882..463006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP447_RS02170 (NP447_02170)	mscL	452008..452418 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
NP447_RS02175 (NP447_02175)	trkA	452548..453924 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
NP447_RS02180 (NP447_02180)	rsmB	453946..455235 (-)	1290	WP_000744780.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
NP447_RS02185 (NP447_02185)	fmt	455281..456228 (-)	948	WP_001402578.1	methionyl-tRNA formyltransferase	-
NP447_RS02190 (NP447_02190)	def	456243..456752 (-)	510	WP_000114984.1	peptide deformylase	-
NP447_RS02195 (NP447_02195)	dprA	456882..458006 (+)	1125	WP_001402665.1	DNA-protecting protein DprA	Machinery gene
NP447_RS02200 (NP447_02200)	smg	457978..458451 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
NP447_RS02205 (NP447_02205)	yrdD	458480..459022 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
NP447_RS02210 (NP447_02210)	tsaC	459027..459599 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
NP447_RS02215 (NP447_02215)	aroE	459604..460422 (+)	819	WP_000451238.1	shikimate dehydrogenase	-
NP447_RS02220 (NP447_02220)	yrdB	460419..460676 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
NP447_RS02225 (NP447_02225)	yrdA	460652..461206 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40992.93 Da Isoelectric Point: 6.3839

                                >NTDB_id=612494 NP447_RS02195 WP_001402665.1 456882..458006(+) (dprA) [Escherichia coli strain QA-1986 630]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=612494 NP447_RS02195 WP_001402665.1 456882..458006(+) (dprA) [Escherichia coli strain QA-1986 630]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.865	98.93	0.444
dprA	Vibrio cholerae strain A1552	44.865	98.93	0.444
dprA	Haemophilus influenzae Rd KW20	45.697	90.107	0.412
dprA	Glaesserella parasuis strain SC1401	45.104	90.107	0.406
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0612494