Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NP443_RS02170 Genome accession   NZ_CP101915
Coordinates   447074..448198 (+) Length   374 a.a.
NCBI ID   WP_057108309.1    Uniprot ID   -
Organism   Escherichia coli strain Evo1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 442074..453198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP443_RS02145 (NP443_02145) mscL 442200..442610 (-) 411 WP_000022439.1 large-conductance mechanosensitive channel protein MscL -
  NP443_RS02150 (NP443_02150) trkA 442740..444116 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  NP443_RS02155 (NP443_02155) rsmB 444138..445427 (-) 1290 WP_201474108.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NP443_RS02160 (NP443_02160) fmt 445473..446420 (-) 948 WP_001402578.1 methionyl-tRNA formyltransferase -
  NP443_RS02165 (NP443_02165) def 446435..446944 (-) 510 WP_000114984.1 peptide deformylase -
  NP443_RS02170 (NP443_02170) dprA 447074..448198 (+) 1125 WP_057108309.1 DNA-protecting protein DprA Machinery gene
  NP443_RS02175 (NP443_02175) smg 448170..448643 (+) 474 WP_000460670.1 DUF494 family protein Smg -
  NP443_RS02180 (NP443_02180) yrdD 448672..449214 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  NP443_RS02185 (NP443_02185) tsaC 449219..449791 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  NP443_RS02190 (NP443_02190) aroE 449796..450614 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  NP443_RS02195 (NP443_02195) yrdB 450611..450868 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  NP443_RS02200 (NP443_02200) yrdA 450844..451398 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  NP443_RS02205 - 451427..451591 (+) 165 WP_256692631.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41013.00 Da        Isoelectric Point: 6.3125

>NTDB_id=612414 NP443_RS02170 WP_057108309.1 447074..448198(+) (dprA) [Escherichia coli strain Evo1]
MVDTEIWLRLMSISSLYGDEMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=612414 NP443_RS02170 WP_057108309.1 447074..448198(+) (dprA) [Escherichia coli strain Evo1]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGAAATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGTCATGCCCGACTGGCTACCAGTTTGCT
TGAACAGGGTGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.355

82.888

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

45.104

90.107

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39