Detailed information NTG0609952

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: I6G24_RS09860
• Genome accession: NZ_CP084189
• Coordinates: 1895186..1897333 (-)
• Length: 715 a.a.
• NCBI ID: WP_023163570.1
• Uniprot ID: A0AAQ0U095
• Organism: Lactococcus lactis strain FDAARGOS_867
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1890186..1902333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G24_RS09825 (I6G24_09830)	-	1890355..1890534 (+)	180	WP_023163574.1	lactococcin family bacteriocin	-
I6G24_RS09830 (I6G24_09835)	-	1890555..1890734 (+)	180	WP_143459874.1	hypothetical protein	-
I6G24_RS09835 (I6G24_09840)	-	1891043..1891705 (+)	663	WP_021214959.1	CPBP family intramembrane glutamic endopeptidase	-
I6G24_RS09840 (I6G24_09845)	-	1891916..1892368 (-)	453	WP_010905102.1	transporter	-
I6G24_RS09845 (I6G24_09850)	-	1892794..1893474 (-)	681	WP_225509962.1	CPBP family intramembrane glutamic endopeptidase	-
I6G24_RS09850 (I6G24_09855)	-	1893519..1893656 (-)	138	WP_021214958.1	lactococcin family bacteriocin	-
I6G24_RS09855 (I6G24_09860)	-	1893933..1895171 (-)	1239	WP_023163571.1	bacteriocin secretion accessory protein	-
I6G24_RS09860 (I6G24_09865)	comA	1895186..1897333 (-)	2148	WP_023163570.1	peptide cleavage/export ABC transporter	Regulator
I6G24_RS09865 (I6G24_09870)	-	1897931..1898521 (-)	591	WP_003132255.1	flavin reductase family protein	-
I6G24_RS09870 (I6G24_09875)	-	1898532..1899701 (-)	1170	WP_010905093.1	ring-cleaving dioxygenase	-
I6G24_RS09875 (I6G24_09880)	-	1899752..1900372 (-)	621	WP_023163569.1	alpha/beta hydrolase	-
I6G24_RS09880 (I6G24_09885)	-	1900403..1900600 (-)	198	WP_010905091.1	DUF4649 domain-containing protein	-
I6G24_RS09885 (I6G24_09890)	-	1900729..1901196 (-)	468	WP_010905090.1	universal stress protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 79879.46 Da
• Isoelectric Point: 8.6006

>NTDB_id=609952 I6G24_RS09860 WP_023163570.1 1895186..1897333(-) (comA) [Lactococcus lactis strain FDAARGOS_867]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAGEGLGFVVQVLRADASLFEMKKV
PYPFIAHVIKNQKYPHYYVITGANKNSVFIADPDPTVKMTKLSKEVFLSEWTGISLFLSPTPSYQPTKEKTSSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVLMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFERQNHEVMQTNAILNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKEAFTLQQSEAIQTAIKTTVQL
VLNVLILWFGATLVMHQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLIPSEFEEKKTELSLSHF
NLNMSEISYQYGFGRKVLSEIKLSIKENEKLTIVGISGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSIMDNLLLGASEATSQEEIIRAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLALDKTIIFIAHRLSVAEMSHRIIVIEQGKVIESGSHSELLAQNGFYAQLYHN

Nucleotide

• Length: 2148 bp

>NTDB_id=609952 I6G24_RS09860 WP_023163570.1 1895186..1897333(-) (comA) [Lactococcus lactis strain FDAARGOS_867]
ATGAAATTTAAAAAGAAAAATTATACCTCCCAAGTAGATGAAATGGATTGTGGATGTGCTGCTTTATCAATGATTTTAAA
ATCCTATGGGACAGAAAAATCGCTTGCCTCTCTTCGTTTACTTGCTGGTACAACAATCGAGGGAACTTCCGCTTTAGGAA
TAAAAAAAGCAGGAGAAGGTTTAGGTTTTGTAGTTCAAGTACTAAGAGCTGATGCAAGCCTTTTTGAAATGAAGAAAGTC
CCTTACCCTTTTATTGCTCATGTCATCAAGAACCAAAAGTATCCACACTACTATGTGATAACTGGCGCAAATAAAAATTC
GGTATTCATCGCAGATCCTGACCCAACCGTTAAAATGACAAAACTTTCAAAAGAAGTTTTCTTATCAGAGTGGACAGGCA
TTAGCTTATTTCTTTCACCTACCCCATCCTATCAGCCCACTAAAGAAAAAACTTCTTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTAATTGCCTCATTCATTGTAACGTTGATTAATATTCTAGGGTCTTA
CTACCTCCAGAGCATGATTGATAGTTACATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACTTATATTATCCAACAAGTCTTAGAGTTTGCTAAGGCTTTCTTACTAAACGTTCTTTCTCAAAGATTAGCCATTGAT
GTCATCCTTTCCTATATTAGACACATTTTCCAACTCCCGATGTCTTTCTTTTCGACTAGAAGAACAGGGGAAATTACCAG
TCGGTTTTCCGATGCCAGTTCTATTTTGGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTAACCATTGTTC
TTATGACAGGACTGATTTTAGGGCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTTTATATTGTT
GTTATTATTATTTTTACTCCGCTTTTTGAAAGACAAAATCATGAAGTTATGCAAACCAATGCCATCTTAAATTCCTCAAT
TATTGAAGACATTAATGGGATTGAAACCATCAAAGCGCTCGCCAGTGAACAAGAGAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAGAGGCTTTCACTTTACAACAGTCAGAAGCCATTCAGACGGCAATAAAAACGACAGTACAACTT
GTACTAAATGTTCTTATTTTATGGTTTGGTGCAACTTTAGTCATGCATCAAAAAATTACCCTCGGACAACTCATTACTTT
TAATGCCTTGCTTTCTTACTTTACAAATCCAATTACTAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTATACCCAGTGAATTTGAAGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AATTTAAACATGTCTGAGATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAAAACTGTCTATTAAAGA
AAATGAAAAGTTGACCATTGTTGGTATAAGCGGTTCAGGGAAGAGTACTCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGTACCATTACTTTAGGTGGAATTGACCTTCAACAGTTTGATAAACATCAACTTCGACGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTCACAGGTTCAATTATGGATAATTTACTTTTAGGCGCTAGTGAAGCTACTTCACAAGA
AGAGATTATTAGAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAATTAGGTTATCAAACTGAACTCT
CAAGTGATGCAAGTAGTTTATCGGGAGGACAAAAACAGAGAATTGCGCTCGCTCGTGCCCTCCTTTCTCCTGCCAAAATA
CTCATCTTAGACGAAGCCACCAGTAATCTTGATATGATTACTGAAAAGAAAATATTAAAGAATTTGTTGGCACTAGATAA
GACAATTATTTTCATTGCTCACCGCCTCTCTGTAGCGGAAATGAGCCATCGTATCATTGTCATTGAACAAGGAAAAGTGA
TAGAAAGTGGTTCACATTCAGAACTGCTTGCTCAAAATGGCTTTTACGCACAACTTTACCATAACTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-437)

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	61.064	99.86	0.61
comA	Streptococcus mitis NCTC 12261	60.084	99.86	0.6
comA	Streptococcus mitis SK321	59.944	99.86	0.599
comA	Streptococcus pneumoniae Rx1	59.664	99.86	0.596
comA	Streptococcus pneumoniae D39	59.664	99.86	0.596
comA	Streptococcus pneumoniae R6	59.664	99.86	0.596
comA	Streptococcus pneumoniae TIGR4	59.384	99.86	0.593
comA/nlmT	Streptococcus mutans UA159	58.635	100	0.589