Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   KE3_RS02365 Genome accession   NC_021900
Coordinates   438227..440137 (+) Length   636 a.a.
NCBI ID   WP_020916311.1    Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 433227..445137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS02350 (KE3_0477) fmt 435205..436140 (+) 936 WP_020916308.1 methionyl-tRNA formyltransferase -
  KE3_RS02355 (KE3_0478) rsmB 436130..437452 (+) 1323 WP_020916309.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KE3_RS02360 (KE3_0479) - 437490..438227 (+) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KE3_RS02365 (KE3_0480) pknB 438227..440137 (+) 1911 WP_020916311.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KE3_RS02370 (KE3_0481) liaF 440238..440933 (+) 696 WP_020916312.1 cell wall-active antibiotics response protein LiaF -
  KE3_RS02375 (KE3_0482) - 440930..441955 (+) 1026 WP_020916313.1 sensor histidine kinase -
  KE3_RS02380 (KE3_0483) - 441939..442583 (+) 645 WP_020916314.1 response regulator -
  KE3_RS11125 (KE3_0484) - 442707..444107 (+) 1401 WP_081048448.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KE3_RS02390 (KE3_0485) - 444107..444463 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 636 a.a.        Molecular weight: 69001.89 Da        Isoelectric Point: 6.5221

>NTDB_id=60814 KE3_RS02365 WP_020916311.1 438227..440137(+) (pknB) [Streptococcus lutetiensis 033]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLTKQKAAKVN
REAVDNKIAKAKTKKKKSHRMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPDVAGTSLQAAKTSLTSAGLKVGRTKG
IYSDTVPSGQVIETNPKAGTSKKEGAKVDIYVSKGTSGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWITGTNYDGG
TIISQTPEKGTKVASEDKITFKVAAIVMPNLIGYTYQDAIAELTALGLSSSHIIVFQADATSSTGYSQVKTPSASAVVVA
QDPYFGASIEGEVNLYFSARSEAQSSEVAPSQSVSESYETSETSESSSLSSSSSSSSSSSSSSTEESSQTDSSSVE

Nucleotide


Download         Length: 1911 bp        

>NTDB_id=60814 KE3_RS02365 WP_020916311.1 438227..440137(+) (pknB) [Streptococcus lutetiensis 033]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAGTCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCACGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATATATTCAAGACCACGCCCC
TCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGAATTGTTC
ACCGTGATTTGAAACCACAAAATATCTTGTTAACCAAAGACGGAACGGTTAAAGTTACCGACTTTGGTATCGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAAACAAACTCAATGCTTGGTAGTGTACACTATTTATCACCTGAACAAGCGCGTGGTTC
AAAAGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATTCCATATGATG
GTGATTCAGCTGTTACGATTGCTCTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTTTGAGTGATCGCTACGCCTCAACTTTTGAAATGAGTCG
TGATTTAATGACTGCTCTCTCATATAACCGTAGCCGCGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACAACAGAACAATTGTTGACAAAACAAAAAGCAGCTAAAGTTAAT
CGTGAAGCTGTGGATAATAAAATTGCAAAAGCGAAAACGAAGAAGAAAAAATCACATCGTATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATCTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAGATGTAGCTGGAACAAGTTTACAAGCTGCTAAGACAAGTCTTACATCAGCAGGACTTAAAGTTGGAAGGACCAAGGGA
ATTTATAGTGATACTGTTCCAAGTGGTCAGGTTATTGAGACTAATCCGAAAGCTGGCACATCTAAGAAAGAAGGTGCCAA
AGTTGACATTTATGTGTCAAAAGGAACATCAGGCTTTAAGATGAAAGATTATACTGGTCAAAACTATCAAGAAGTTATCA
AAGAACTCAAAGATAAACACGGTATTTCAAGTGATAAGATTGATGTTGAATGGATAACAGGCACTAACTATGATGGTGGT
ACTATCATTAGTCAAACACCTGAAAAAGGTACAAAAGTTGCTAGTGAAGATAAGATTACTTTCAAGGTTGCAGCAATCGT
TATGCCAAACCTTATTGGTTATACTTATCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGTTCGCATATTA
TAGTATTCCAAGCAGATGCTACTTCATCAACTGGATATTCTCAAGTTAAAACACCATCTGCCTCTGCAGTTGTTGTGGCA
CAAGATCCTTACTTTGGCGCATCTATTGAAGGAGAGGTTAACCTTTACTTCTCAGCTAGAAGTGAAGCTCAGTCTTCAGA
AGTTGCACCATCTCAATCTGTTTCTGAGTCATATGAGACAAGTGAAACTAGTGAGTCAAGTTCTTTAAGCAGCAGCAGTA
GCAGTAGTAGCAGTAGTAGCAGTAGCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-247)

PASTA domain (PASTA)

(507-578)

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-503)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.505

90.252

0.591
  stkP/pknB Streptococcus salivarius strain HSISS4

62.479

92.61

0.579
  stkP Streptococcus pneumoniae TIGR4

58.945

83.491

0.492
  stkP Streptococcus pneumoniae D39

58.757

83.491

0.491
  stkP Streptococcus pneumoniae R6

58.757

83.491

0.491
  stkP Streptococcus pneumoniae Rx1

58.569

83.491

0.489

Multiple sequence alignment