Detailed information NTG0607840

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: LAZ98_RS13490
• Genome accession: NZ_CP083764
• Coordinates: 2665596..2666210 (-)
• Length: 204 a.a.
• NCBI ID: WP_224443291.1
• Uniprot ID: -
• Organism: Bacillus velezensis strain DMB07
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2660596..2671210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LAZ98_RS13460 (LAZ98_13460)	rpsT	2660899..2661165 (+)	267	WP_003152876.1	30S ribosomal protein S20	-
LAZ98_RS13465 (LAZ98_13465)	holA	2661182..2662223 (-)	1042	Protein_2613	DNA polymerase III subunit delta	-
LAZ98_RS13470 (LAZ98_13470)	-	2662263..2662414 (-)	152	Protein_2614	hypothetical protein	-
LAZ98_RS13475 (LAZ98_13475)	-	2662455..2662589 (+)	135	WP_003152870.1	YqzM family protein	-
LAZ98_RS13480 (LAZ98_13480)	comEC	2662608..2664959 (-)	2352	WP_151140321.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LAZ98_RS13485 (LAZ98_13485)	-	2664960..2665529 (-)	570	WP_003152868.1	ComE operon protein 2	-
LAZ98_RS13490 (LAZ98_13490)	comEA	2665596..2666210 (-)	615	WP_224443291.1	helix-hairpin-helix domain-containing protein	Machinery gene
LAZ98_RS13495 (LAZ98_13495)	comER	2666269..2667090 (+)	822	WP_012118027.1	late competence protein ComER	-
LAZ98_RS13500 (LAZ98_13500)	-	2667159..2667896 (-)	738	WP_015417856.1	class I SAM-dependent methyltransferase	-
LAZ98_RS13505 (LAZ98_13505)	rsfS	2667893..2668249 (-)	357	WP_003152864.1	ribosome silencing factor	-
LAZ98_RS13510 (LAZ98_13510)	yqeK	2668246..2668827 (-)	582	WP_017418181.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
LAZ98_RS13515 (LAZ98_13515)	-	2668817..2669386 (-)	570	WP_017418182.1	nicotinate-nucleotide adenylyltransferase	-
LAZ98_RS13520 (LAZ98_13520)	yhbY	2669397..2669687 (-)	291	WP_003152858.1	ribosome assembly RNA-binding protein YhbY	-
LAZ98_RS13525 (LAZ98_13525)	aroE	2669681..2670523 (-)	843	WP_017418183.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22131.20 Da
• Isoelectric Point: 5.1985

>NTDB_id=607840 LAZ98_RS13490 WP_224443291.1 2665596..2666210(-) (comEA) [Bacillus velezensis strain DMB07]
MTKAMMTEPLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKDTADDKIMIDVKGAVRNPGVY
EMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVYIPSEGEEENHPKTAAGEKENAAVNINTASLDELQAISGVG
QKKAEAIIAYREENGRFQTAEDLMNVSGFGEKSFERIKTSITVK

Nucleotide

• Length: 615 bp

>NTDB_id=607840 LAZ98_RS13490 WP_224443291.1 2665596..2666210(-) (comEA) [Bacillus velezensis strain DMB07]
ATGACGAAAGCGATGATGACGGAGCCGCTGCGGCGGAACCTGAAAATTCTGGGCGCTTGTCTTGCTGCAGGAGCGGTTTT
TATCTGTATTTGGCTGTTTCGTTCTGAAAAGGAAGAGCCGGTCAAACAGCAGTCCGTGCTCGGCCAAACAGCCTCGGCAT
CCGTCGCGGACAAAAAAGACACCGCAGACGATAAGATTATGATTGATGTGAAAGGCGCGGTCCGAAATCCCGGCGTGTAT
GAAATGAAAGCGGGAGACAGAGTGACGCAAGCCATTGAAAAAGCCGGAGGCCTGAAGAAAAAGGCGGATGAATTGAATGT
TAATTTAGCAGAGCAGCTGCAGGACGGGACGATTGTTTATATTCCGAGTGAAGGCGAAGAAGAGAATCACCCGAAAACAG
CAGCGGGTGAAAAGGAGAATGCAGCTGTCAATATCAATACGGCATCTTTGGACGAACTTCAGGCGATTTCCGGGGTGGGG
CAGAAAAAAGCGGAAGCCATTATCGCCTACCGAGAAGAAAACGGACGGTTTCAGACTGCTGAAGATTTGATGAATGTATC
AGGCTTTGGAGAAAAGTCATTTGAGCGGATAAAAACTTCCATTACGGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (141-202)

• SLBB domain (SLBB) (68-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	58.854	94.118	0.554
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae Rx1	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae D39	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae R6	35.545	100	0.368
comEA/celA/cilE	Streptococcus mitis SK321	35.071	100	0.363