Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   K9N66_RS13730 Genome accession   NZ_CP083695
Coordinates   2879865..2881169 (-) Length   434 a.a.
NCBI ID   WP_224434427.1    Uniprot ID   -
Organism   Enterococcus mundtii strain P6     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2881598..2897549 2879865..2881169 flank 429


Gene organization within MGE regions


Location: 2879865..2897549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K9N66_RS13730 (K9N66_13730) htrA 2879865..2881169 (-) 1305 WP_224434427.1 S1C family serine protease Regulator
  K9N66_RS13735 (K9N66_13735) rlmH 2881598..2882077 (+) 480 WP_010736523.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  K9N66_RS13740 (K9N66_13740) - 2882175..2884223 (+) 2049 WP_224434428.1 hypothetical protein -
  K9N66_RS13745 (K9N66_13745) - 2884204..2884488 (+) 285 WP_002324314.1 hypothetical protein -
  K9N66_RS13750 (K9N66_13750) - 2884648..2884956 (+) 309 WP_224434429.1 DUF960 domain-containing protein -
  K9N66_RS13755 (K9N66_13755) - 2884983..2885282 (+) 300 WP_002340122.1 hypothetical protein -
  K9N66_RS13760 (K9N66_13760) - 2885456..2886007 (+) 552 WP_002344691.1 DUF1643 domain-containing protein -
  K9N66_RS13765 (K9N66_13765) - 2886153..2886446 (+) 294 WP_104776419.1 Mor transcription activator family protein -
  K9N66_RS13770 (K9N66_13770) - 2886439..2886609 (+) 171 WP_224434430.1 hypothetical protein -
  K9N66_RS13775 (K9N66_13775) - 2886790..2887704 (+) 915 WP_104776420.1 DUF4767 domain-containing protein -
  K9N66_RS13780 (K9N66_13780) fic 2888303..2888908 (+) 606 WP_045172145.1 protein adenylyltransferase Fic -
  K9N66_RS13785 (K9N66_13785) - 2889437..2890486 (+) 1050 WP_104776421.1 hypothetical protein -
  K9N66_RS13790 (K9N66_13790) - 2890634..2892280 (+) 1647 WP_104879359.1 DUF927 domain-containing protein -
  K9N66_RS13795 (K9N66_13795) - 2892459..2892698 (+) 240 WP_104776423.1 hypothetical protein -
  K9N66_RS13800 (K9N66_13800) - 2892714..2894087 (+) 1374 WP_137206946.1 recombinase family protein -
  K9N66_RS13810 (K9N66_13810) - 2894091..2895726 (+) 1636 Protein_2687 recombinase family protein -
  K9N66_RS13815 (K9N66_13815) - 2895978..2897549 (+) 1572 WP_104776426.1 DNA cytosine methyltransferase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 45138.05 Da        Isoelectric Point: 4.4469

>NTDB_id=607326 K9N66_RS13730 WP_224434427.1 2879865..2881169(-) (htrA) [Enterococcus mundtii strain P6]
MDRRDVTPKMKKRKSNGIWRKLGLGVVGGVIGGLLTFGIFYAATGGGNSVTTSSSSGTQNASGETVVENVKVNVDSDITS
AVDKVQGAVVSVINLQKQSSSSDPFGSLFGQQQESSDEDGELQAYSEGSGVIYKKEGGSAYIVTNNHVVDGQQGLEVLLK
DGTKVKAELVGTDAYTDLAVLKISADKVDTVASFGDSASLKVGEPAIAIGSPLGSQYANSVTSGIISSLNRQVTSTNESN
ETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSDSSSVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMTDLSAVSTQQQEQILKLPSSVTNGVIIRSVQPATPAEKAGLEQYDVITKIDDTEVSSGVELQSVLYGKKVGDTVKIT
YYRGEEEKTVDIKLTIDNTALNQGNSNSSNGSNN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=607326 K9N66_RS13730 WP_224434427.1 2879865..2881169(-) (htrA) [Enterococcus mundtii strain P6]
ATGGACAGAAGAGATGTGACACCAAAAATGAAAAAAAGAAAATCTAATGGCATTTGGCGAAAGCTAGGTCTTGGCGTAGT
TGGTGGCGTGATTGGCGGATTACTGACTTTCGGTATTTTTTATGCAGCAACTGGAGGTGGTAACTCAGTAACGACTTCTT
CTAGCAGTGGGACACAAAATGCATCAGGCGAAACAGTTGTCGAAAATGTAAAAGTCAATGTAGATTCAGATATCACTTCT
GCAGTAGATAAAGTGCAAGGCGCAGTTGTTTCTGTTATCAACCTACAAAAACAAAGTTCATCATCTGACCCGTTTGGTTC
ATTATTTGGCCAACAACAAGAAAGTAGTGACGAAGATGGCGAATTGCAAGCTTACAGTGAAGGTAGCGGTGTGATCTATA
AAAAAGAGGGCGGTTCCGCTTATATCGTGACGAATAATCACGTGGTCGATGGACAACAAGGGTTAGAAGTTTTATTAAAA
GATGGAACAAAAGTGAAAGCAGAATTAGTCGGTACAGATGCTTACACTGATTTAGCTGTGTTGAAAATCAGTGCTGACAA
AGTCGACACTGTTGCTTCATTTGGCGATTCTGCTTCATTGAAAGTCGGCGAACCTGCGATTGCGATTGGTTCTCCTCTAG
GTTCTCAATACGCGAATTCCGTAACATCAGGGATCATTTCTTCCTTGAATCGCCAAGTGACAAGTACCAATGAATCTAAT
GAAACGGTCAATATCAACGCGATTCAAACAGATGCAGCGATCAACCCGGGGAACTCTGGTGGTCCACTAGTTAATATCGA
AGGACAAGTCATTGGTATCAATTCAAGTAAAATTGCATCGACTTCTGATTCTTCAAGTGTAAGTGTTGAAGGAATGGGCT
TTGCGATTCCAAGTAATGATGTCGTAAATATCATCAATCAACTTGAAAAAGATGGAAAAGTAACACGCCCTGCACTGGGT
ATCACAATGACCGATCTTTCCGCCGTTTCTACACAACAACAGGAACAGATCTTGAAATTACCATCTTCTGTAACAAATGG
CGTGATCATTCGTTCGGTTCAACCAGCAACGCCTGCGGAAAAAGCTGGCTTAGAACAATATGATGTCATCACAAAAATCG
ATGATACAGAAGTCTCATCTGGTGTTGAATTACAGTCTGTGCTTTATGGTAAAAAAGTTGGTGACACTGTGAAGATCACT
TATTACCGTGGCGAAGAAGAAAAAACTGTAGATATCAAATTGACAATTGATAATACTGCATTAAATCAAGGAAATTCAAA
TAGTTCCAATGGCTCAAATAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(128-273)

PDZ domain (PDZ_2)

(317-414)

Peptidase family M50 (Peptidase_M50)

(13-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.01

90.092

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

53.102

92.857

0.493
  htrA Streptococcus mitis NCTC 12261

53.03

91.244

0.484
  htrA Streptococcus pneumoniae Rx1

58.929

77.419

0.456
  htrA Streptococcus pneumoniae D39

58.929

77.419

0.456
  htrA Streptococcus pneumoniae R6

58.929

77.419

0.456
  htrA Streptococcus pneumoniae TIGR4

58.929

77.419

0.456