Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NMD56_RS02195 Genome accession   NZ_CP100901
Coordinates   454348..455472 (+) Length   374 a.a.
NCBI ID   WP_001402665.1    Uniprot ID   -
Organism   Escherichia coli strain ET826     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 449348..460472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD56_RS02170 (NMD56_02165) mscL 449474..449884 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  NMD56_RS02175 (NMD56_02170) trkA 450014..451390 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  NMD56_RS02180 (NMD56_02175) rsmB 451412..452701 (-) 1290 WP_000744780.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NMD56_RS02185 (NMD56_02180) fmt 452747..453694 (-) 948 WP_001402578.1 methionyl-tRNA formyltransferase -
  NMD56_RS02190 (NMD56_02185) def 453709..454218 (-) 510 WP_000114984.1 peptide deformylase -
  NMD56_RS02195 (NMD56_02190) dprA 454348..455472 (+) 1125 WP_001402665.1 DNA-protecting protein DprA Machinery gene
  NMD56_RS02200 (NMD56_02195) smg 455444..455917 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  NMD56_RS02205 (NMD56_02200) yrdD 455946..456488 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  NMD56_RS02210 (NMD56_02205) tsaC 456493..457065 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  NMD56_RS02215 (NMD56_02210) aroE 457070..457888 (+) 819 WP_000451238.1 shikimate dehydrogenase -
  NMD56_RS02220 (NMD56_02215) yrdB 457885..458142 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  NMD56_RS02225 (NMD56_02220) yrdA 458118..458672 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40992.93 Da        Isoelectric Point: 6.3839

>NTDB_id=606523 NMD56_RS02195 WP_001402665.1 454348..455472(+) (dprA) [Escherichia coli strain ET826]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=606523 NMD56_RS02195 WP_001402665.1 454348..455472(+) (dprA) [Escherichia coli strain ET826]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.865

98.93

0.444
  dprA Vibrio cholerae strain A1552

44.865

98.93

0.444
  dprA Haemophilus influenzae Rd KW20

45.697

90.107

0.412
  dprA Glaesserella parasuis strain SC1401

45.104

90.107

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393