Detailed information    

insolico Bioinformatically predicted

Overview


Name   comA   Type   Regulator
Locus tag   N134_RS09935 Genome accession   NC_021872
Coordinates   2120339..2120638 (+) Length   99 a.a.
NCBI ID   WP_020843448.1    Uniprot ID   S5N8C6
Organism   Limosilactobacillus reuteri TD1     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 2115339..2125638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N134_RS09905 (N134_10140) - 2115770..2116447 (+) 678 WP_019254113.1 dihydrofolate reductase family protein -
  N134_RS09910 (N134_10145) - 2116661..2116969 (-) 309 WP_019254112.1 hypothetical protein -
  N134_RS09920 (N134_10155) - 2117508..2117993 (+) 486 WP_019254110.1 DUF3278 domain-containing protein -
  N134_RS09925 (N134_10160) - 2118480..2119541 (+) 1062 WP_019254109.1 GHKL domain-containing protein -
  N134_RS09930 (N134_10165) - 2119554..2120327 (+) 774 WP_019254108.1 LytTR family DNA-binding domain-containing protein -
  N134_RS09935 (N134_10170) comA 2120339..2120638 (+) 300 WP_020843448.1 cysteine peptidase family C39 domain-containing protein Regulator
  N134_RS09940 (N134_10175) - 2120900..2121226 (-) 327 WP_019253437.1 type II toxin-antitoxin system PemK/MazF family toxin -
  N134_RS09945 (N134_10180) - 2121216..2121476 (-) 261 WP_019253436.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  N134_RS09950 (N134_10185) - 2121720..2122214 (+) 495 WP_019253435.1 prolyl-tRNA synthetase associated domain-containing protein -
  N134_RS09955 (N134_10190) arsC 2122574..2122984 (+) 411 WP_019253434.1 arsenate reductase (thioredoxin) -
  N134_RS09960 (N134_10195) - 2123054..2124073 (-) 1020 WP_003665187.1 serine hydrolase -
  N134_RS09965 (N134_10200) hpt 2124287..2124823 (+) 537 WP_003665189.1 hypoxanthine phosphoribosyltransferase -
  N134_RS09970 (N134_10205) - 2124981..2125631 (+) 651 WP_042229611.1 MgtC/SapB family protein -

Sequence


Protein


Download         Length: 99 a.a.        Molecular weight: 11046.78 Da        Isoelectric Point: 8.8454

>NTDB_id=60634 N134_RS09935 WP_020843448.1 2120339..2120638(+) (comA) [Limosilactobacillus reuteri TD1]
MYNFRRHYINQVDEADCGVAALAMILHNYGSKISLATLRKFTKTTTDGTTALGIVKAAKKLKMDVEAYQADASLFDSKDV
IYPFIADPDIQVKRIPSVF

Nucleotide


Download         Length: 300 bp        

>NTDB_id=60634 N134_RS09935 WP_020843448.1 2120339..2120638(+) (comA) [Limosilactobacillus reuteri TD1]
ATGTATAACTTTAGAAGACACTATATAAATCAAGTGGATGAAGCTGATTGTGGAGTAGCAGCACTAGCAATGATTCTTCA
TAATTACGGCTCTAAAATTTCATTAGCAACTCTGCGAAAATTTACAAAAACCACTACTGATGGAACTACTGCACTTGGGA
TTGTAAAAGCAGCAAAAAAGTTAAAAATGGATGTTGAAGCATATCAAGCAGATGCTAGTTTATTTGATTCAAAAGATGTA
ATTTATCCTTTTATTGCTGATCCTGATATACAAGTTAAACGTATTCCTTCAGTATTTTAA

Domains


Predicted by InterproScan.

(6-86)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB S5N8C6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

62.195

82.828

0.515

  comA Streptococcus mitis SK321

54.878

82.828

0.455

  comA Streptococcus mitis NCTC 12261

54.878

82.828

0.455

  comA Streptococcus pneumoniae Rx1

53.659

82.828

0.444

  comA Streptococcus pneumoniae D39

53.659

82.828

0.444

  comA Streptococcus pneumoniae R6

53.659

82.828

0.444

  comA Streptococcus pneumoniae TIGR4

53.659

82.828

0.444

  comA/nlmT Streptococcus mutans UA159

52.381

84.848

0.444


Multiple sequence alignment