Detailed information NTG0602550

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: K8B76_RS07745
• Genome accession: NZ_CP082820
• Coordinates: 1582304..1584283 (-)
• Length: 659 a.a.
• NCBI ID: WP_223080571.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SCAID PHRX1-2021
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1577304..1589283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B76_RS07715 (K8B76_07715)	-	1577400..1578674 (-)	1275	WP_000704380.1	hydroxymethylglutaryl-CoA reductase, degradative	-
K8B76_RS07720 (K8B76_07720)	-	1578674..1579846 (-)	1173	WP_000151958.1	hydroxymethylglutaryl-CoA synthase	-
K8B76_RS07725 (K8B76_07725)	-	1579977..1580225 (-)	249	WP_001813143.1	hypothetical protein	-
K8B76_RS07730 (K8B76_07730)	-	1580293..1580918 (-)	626	Protein_1550	IS5 family transposase	-
K8B76_RS07735 (K8B76_07735)	-	1580980..1581429 (-)	450	WP_000176924.1	threonine/serine exporter family protein	-
K8B76_RS07740 (K8B76_07740)	-	1581431..1582189 (-)	759	WP_000392880.1	threonine/serine exporter ThrE family protein	-
K8B76_RS07745 (K8B76_07745)	stkP	1582304..1584283 (-)	1980	WP_223080571.1	serine/threonine-protein kinase StkP	Regulator
K8B76_RS07750 (K8B76_07750)	-	1584280..1585020 (-)	741	WP_000406248.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
K8B76_RS07755 (K8B76_07755)	rsmB	1585035..1586348 (-)	1314	WP_001814363.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
K8B76_RS07760 (K8B76_07760)	fmt	1586341..1587276 (-)	936	WP_000163685.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 659 a.a.
• Molecular weight: 72385.97 Da
• Isoelectric Point: 9.2260

>NTDB_id=602550 K8B76_RS07745 WP_223080571.1 1582304..1584283(-) (stkP) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDRAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide

• Length: 1980 bp

>NTDB_id=602550 K8B76_RS07745 WP_223080571.1 1582304..1584283(-) (stkP) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACGGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGAGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTA
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (440-505)

• PASTA domain (PASTA) (582-651)

• PASTA domain (PASTA) (513-577)

• PASTA domain (PASTA) (371-432)

• Protein kinase domain (Pkinase) (12-227)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	99.697	100	0.997
stkP	Streptococcus pneumoniae D39	99.545	100	0.995
stkP	Streptococcus pneumoniae R6	99.545	100	0.995
stkP	Streptococcus pneumoniae Rx1	99.393	100	0.994
pknB	Streptococcus mutans UA159	52.479	88.771	0.466
stkP/pknB	Streptococcus salivarius strain HSISS4	51.635	88.164	0.455