Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   JSY00_RS02125 Genome accession   NZ_CP082778
Coordinates   418035..420029 (+) Length   664 a.a.
NCBI ID   WP_044692308.1    Uniprot ID   A0A123SU34
Organism   Streptococcus suis strain ID32098     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 413035..425029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JSY00_RS02110 (JSY00_02110) fmt 415022..415960 (+) 939 WP_044668906.1 methionyl-tRNA formyltransferase -
  JSY00_RS02115 (JSY00_02115) rsmB 415947..417260 (+) 1314 WP_079393948.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  JSY00_RS02120 (JSY00_02120) - 417298..418035 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  JSY00_RS02125 (JSY00_02125) stkP 418035..420029 (+) 1995 WP_044692308.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  JSY00_RS02130 (JSY00_02130) liaF 420352..421011 (+) 660 WP_228475102.1 cell wall-active antibiotics response protein LiaF -
  JSY00_RS02135 (JSY00_02135) - 421008..422024 (+) 1017 WP_044668898.1 sensor histidine kinase -
  JSY00_RS02140 (JSY00_02140) - 421996..422637 (+) 642 WP_002937025.1 response regulator transcription factor -
  JSY00_RS02145 (JSY00_02145) - 422687..424087 (+) 1401 WP_044668895.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  JSY00_RS02150 (JSY00_02150) - 424089..424460 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71422.01 Da        Isoelectric Point: 6.3011

>NTDB_id=602093 JSY00_RS02125 WP_044692308.1 418035..420029(+) (stkP) [Streptococcus suis strain ID32098]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATIDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYISKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=602093 JSY00_RS02125 WP_044692308.1 418035..420029(+) (stkP) [Streptococcus suis strain ID32098]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCAATGGGGATCATCCTTTTTGAAATGTTGACAGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATTGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAGGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAGGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACCG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTATAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTACATTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCTGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTGACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAGCACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGTACCAGTAGCGATTCCTCAACAGGAAGTTCCACTAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(574-638)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123SU34

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.932

97.59

0.517
  stkP Streptococcus pneumoniae D39

52.778

97.59

0.515
  stkP Streptococcus pneumoniae R6

52.778

97.59

0.515
  stkP Streptococcus pneumoniae Rx1

52.623

97.59

0.514
  stkP/pknB Streptococcus salivarius strain HSISS4

52.308

88.102

0.461
  pknB Streptococcus mutans UA159

54.579

80.572

0.44