Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV/pilI   Type   Regulator
Locus tag   NDL72_RS02675 Genome accession   NZ_CP098505
Coordinates   517769..518383 (+) Length   204 a.a.
NCBI ID   WP_012503479.1    Uniprot ID   B4RKG4
Organism   Neisseria gonorrhoeae strain 10536     
Function   repress natural transformation; antagonize ComP (predicted from homology)   
Competence regulation

Genomic Context

Location: 512769..523383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NDL72_RS02650 (NDL72_02630) - 513267..513599 (+) 333 WP_003687908.1 hypothetical protein -
  NDL72_RS02655 (NDL72_02635) - 513929..514438 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NDL72_RS02660 (NDL72_02640) - 514670..515251 (-) 582 WP_003690895.1 superoxide dismutase -
  NDL72_RS02665 (NDL72_02645) dnaB 515415..516818 (+) 1404 WP_012503477.1 replicative DNA helicase -
  NDL72_RS12060 - 516812..516924 (-) 113 Protein_519 IS5/IS1182 family transposase -
  NDL72_RS02670 (NDL72_02650) pilH 517075..517737 (+) 663 WP_041421240.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NDL72_RS02675 (NDL72_02655) pilV/pilI 517769..518383 (+) 615 WP_012503479.1 type IV pilus modification protein PilV Regulator
  NDL72_RS02680 (NDL72_02660) pilJ 518380..519339 (+) 960 WP_260247272.1 PilW family protein Machinery gene
  NDL72_RS02685 (NDL72_02665) pilK 519318..519917 (+) 600 WP_260247273.1 pilus assembly protein Machinery gene
  NDL72_RS02690 (NDL72_02670) pilL 519932..520405 (+) 474 WP_012503482.1 PilX family type IV pilin Machinery gene
  NDL72_RS02695 (NDL72_02675) - 520475..520783 (-) 309 WP_003706588.1 AzlD family protein -
  NDL72_RS02700 (NDL72_02680) - 520780..521491 (-) 712 Protein_526 AzlC family ABC transporter permease -
  NDL72_RS02705 (NDL72_02685) dut 521657..522109 (+) 453 WP_003701071.1 dUTP diphosphatase -
  NDL72_RS02710 (NDL72_02690) dapC 522181..523368 (+) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -

Sequence

Protein


Download         Length: 204 a.a.        Molecular weight: 22099.99 Da        Isoelectric Point: 4.9673

>NTDB_id=600245 NDL72_RS02675 WP_012503479.1 517769..518383(+) (pilV/pilI) [Neisseria gonorrhoeae strain 10536]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTGPYTPTPSGGDFKLNNNNLISKKDLAKAQLDRFDYELRNALPDAVAIHYAVCKDSSGGAPTLSGGTFSPNCDNKA
NGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGHE

Nucleotide


Download         Length: 615 bp        

>NTDB_id=600245 NDL72_RS02675 WP_012503479.1 517769..518383(+) (pilV/pilI) [Neisseria gonorrhoeae strain 10536]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACGGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGGGCCGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGCTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGATTATGAATTGAGAAACGCCTTGCCGGATGCGGTAGCTATTCATT
ACGCCGTCTGCAAGGATTCGTCGGGTGGCGCGCCGACATTGTCCGGCGGTACTTTTTCTCCAAATTGCGATAATAAGGCA
AACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAGGT
GAGCGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCATGAATGA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RKG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV/pilI Neisseria gonorrhoeae MS11

90.686

100

0.907
  pilV Neisseria meningitidis 8013

84.135

100

0.858