Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K6973_RS02015 Genome accession   NZ_CP082206
Coordinates   369575..370336 (+) Length   253 a.a.
NCBI ID   WP_138124792.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain DY107     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 364575..375336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6973_RS02000 (K6973_02000) - 364834..366402 (-) 1569 WP_218655071.1 ABC transporter substrate-binding protein/permease -
  K6973_RS02005 (K6973_02005) - 366601..368526 (+) 1926 WP_222819498.1 DUF2207 domain-containing protein -
  K6973_RS02010 (K6973_02010) - 368592..369431 (+) 840 WP_218655073.1 undecaprenyl-diphosphate phosphatase -
  K6973_RS02015 (K6973_02015) mecA 369575..370336 (+) 762 WP_138124792.1 adaptor protein MecA Regulator
  K6973_RS02020 (K6973_02020) - 370343..371512 (+) 1170 WP_218655074.1 MraY family glycosyltransferase -
  K6973_RS02025 (K6973_02025) sufC 371625..372395 (+) 771 WP_218655075.1 Fe-S cluster assembly ATPase SufC -
  K6973_RS02030 (K6973_02030) sufD 372492..373754 (+) 1263 WP_218655076.1 Fe-S cluster assembly protein SufD -
  K6973_RS02035 (K6973_02035) - 373785..375011 (+) 1227 WP_218655077.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.68 Da        Isoelectric Point: 4.0755

>NTDB_id=600083 K6973_RS02015 WP_138124792.1 369575..370336(+) (mecA) [Streptococcus dysgalactiae strain DY107]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPEPLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=600083 K6973_RS02015 WP_138124792.1 369575..370336(+) (mecA) [Streptococcus dysgalactiae strain DY107]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAGACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGATCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTGGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGAGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482