Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K6969_RS10440 Genome accession   NZ_CP082205
Coordinates   2173337..2174059 (-) Length   240 a.a.
NCBI ID   WP_029173866.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2168337..2179059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS10425 (K6969_10315) sufD 2169453..2170715 (-) 1263 WP_029173863.1 Fe-S cluster assembly protein SufD -
  K6969_RS10430 (K6969_10320) sufC 2170732..2171505 (-) 774 WP_029173864.1 Fe-S cluster assembly ATPase SufC -
  K6969_RS10435 (K6969_10325) - 2172168..2173340 (-) 1173 WP_029173865.1 glycosyltransferase family 4 protein -
  K6969_RS10440 (K6969_10330) mecA 2173337..2174059 (-) 723 WP_029173866.1 adaptor protein MecA Regulator
  K6969_RS10445 (K6969_10335) - 2174187..2175026 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  K6969_RS10450 (K6969_10340) - 2175150..2176715 (+) 1566 WP_029173867.1 ABC transporter substrate-binding protein/permease -
  K6969_RS10455 (K6969_10345) - 2176708..2177451 (+) 744 WP_024381054.1 amino acid ABC transporter ATP-binding protein -
  K6969_RS10460 (K6969_10350) - 2177580..2177789 (-) 210 WP_009910800.1 hypothetical protein -
  K6969_RS10465 (K6969_10355) - 2177875..2178777 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28051.58 Da        Isoelectric Point: 4.0533

>NTDB_id=600065 K6969_RS10440 WP_029173866.1 2173337..2174059(-) (mecA) [Streptococcus suis strain AKJ18]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPEEFFKSLEQTVREKSTPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=600065 K6969_RS10440 WP_029173866.1 2173337..2174059(-) (mecA) [Streptococcus suis strain AKJ18]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGAGGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCACACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTACATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

50.82

100

0.517
  mecA Streptococcus pneumoniae D39

50.82

100

0.517
  mecA Streptococcus pneumoniae R6

50.82

100

0.517
  mecA Streptococcus pneumoniae TIGR4

50.82

100

0.517
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471