Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   K6969_RS00875 Genome accession   NZ_CP082205
Coordinates   160126..161028 (+) Length   300 a.a.
NCBI ID   WP_024399278.1    Uniprot ID   A0A0M9FKU5
Organism   Streptococcus suis strain AKJ18     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 155126..166028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS00850 (K6969_00825) - 156198..157304 (+) 1107 WP_321537434.1 MerR family transcriptional regulator -
  K6969_RS00855 (K6969_00830) - 157277..157456 (+) 180 WP_321537435.1 hypothetical protein -
  K6969_RS00860 (K6969_00835) ruvB 157650..158651 (+) 1002 WP_024377694.1 Holliday junction branch migration DNA helicase RuvB -
  K6969_RS00865 (K6969_00840) - 158651..159397 (+) 747 WP_171942860.1 GNAT family N-acetyltransferase -
  K6969_RS00870 (K6969_00845) - 159399..160022 (+) 624 WP_171942861.1 HAD-IA family hydrolase -
  K6969_RS00875 (K6969_00850) comR 160126..161028 (+) 903 WP_024399278.1 helix-turn-helix domain-containing protein Regulator
  K6969_RS00880 (K6969_00855) - 161593..162813 (+) 1221 WP_029173231.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  K6969_RS00885 (K6969_00860) - 163004..164527 (+) 1524 WP_029173230.1 quinol oxidase -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35179.23 Da        Isoelectric Point: 4.3840

>NTDB_id=600022 K6969_RS00875 WP_024399278.1 160126..161028(+) (comR) [Streptococcus suis strain AKJ18]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIQLYLINLRMEVKQSSDFQHFLDLVEKLPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide


Download         Length: 903 bp        

>NTDB_id=600022 K6969_RS00875 WP_024399278.1 160126..161028(+) (comR) [Streptococcus suis strain AKJ18]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAACTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAGTATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTTCAGCACTTTTTAGACTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACC
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCTGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCCCACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FKU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.224

99.667

0.67
  comR Streptococcus suis 05ZYH33

67.224

99.667

0.67
  comR Streptococcus suis D9

61.13

100

0.613
  comR Streptococcus mutans UA159

43.478

99.667

0.433
  comR Streptococcus pyogenes MGAS8232

40.203

98.667

0.397
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.69

96.667

0.393