Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K6974_RS10975 Genome accession   NZ_CP082204
Coordinates   2199544..2200266 (-) Length   240 a.a.
NCBI ID   WP_105128825.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2194544..2205266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS10960 (K6974_10850) sufD 2195678..2196940 (-) 1263 WP_222337053.1 Fe-S cluster assembly protein SufD -
  K6974_RS10965 (K6974_10855) sufC 2196957..2197730 (-) 774 WP_222337052.1 Fe-S cluster assembly ATPase SufC -
  K6974_RS10970 (K6974_10860) - 2198375..2199547 (-) 1173 WP_105112683.1 glycosyltransferase family 4 protein -
  K6974_RS10975 (K6974_10865) mecA 2199544..2200266 (-) 723 WP_105128825.1 adaptor protein MecA Regulator
  K6974_RS10980 (K6974_10870) - 2200394..2201233 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  K6974_RS10985 (K6974_10875) - 2201356..2202921 (+) 1566 WP_222337051.1 ABC transporter substrate-binding protein/permease -
  K6974_RS10990 (K6974_10880) - 2202914..2203657 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  K6974_RS10995 (K6974_10885) - 2203785..2203994 (-) 210 WP_009910800.1 hypothetical protein -
  K6974_RS11000 (K6974_10890) - 2204080..2204982 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28033.56 Da        Isoelectric Point: 4.0170

>NTDB_id=600010 K6974_RS10975 WP_105128825.1 2199544..2200266(-) (mecA) [Streptococcus suis strain FJSM5]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGYYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=600010 K6974_RS10975 WP_105128825.1 2199544..2200266(-) (mecA) [Streptococcus suis strain FJSM5]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTTACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACATGGAACTTTGATGCTTCCACTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.083

100

0.471
  mecA Streptococcus thermophilus LMG 18311

46.667

100

0.467