Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K6972_RS08960 Genome accession   NZ_CP082203
Coordinates   1827496..1828218 (-) Length   240 a.a.
NCBI ID   WP_222812530.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1822496..1833218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS08940 (K6972_08940) - 1822652..1823875 (-) 1224 WP_222812529.1 cysteine desulfurase -
  K6972_RS08945 (K6972_08945) sufD 1823879..1825141 (-) 1263 WP_024406545.1 Fe-S cluster assembly protein SufD -
  K6972_RS08950 (K6972_08950) sufC 1825158..1825931 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  K6972_RS08955 (K6972_08955) - 1826327..1827499 (-) 1173 WP_024414291.1 glycosyltransferase family 4 protein -
  K6972_RS08960 (K6972_08960) mecA 1827496..1828218 (-) 723 WP_222812530.1 adaptor protein MecA Regulator
  K6972_RS08965 (K6972_08965) - 1828346..1829182 (-) 837 WP_024410806.1 undecaprenyl-diphosphate phosphatase -
  K6972_RS08970 (K6972_08970) - 1829309..1830874 (+) 1566 WP_024393418.1 ABC transporter substrate-binding protein/permease -
  K6972_RS08975 (K6972_08975) - 1830867..1831610 (+) 744 WP_222812531.1 amino acid ABC transporter ATP-binding protein -
  K6972_RS08980 (K6972_08980) - 1831734..1831943 (-) 210 WP_009910800.1 hypothetical protein -
  K6972_RS08985 (K6972_08985) - 1832029..1832931 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=599952 K6972_RS08960 WP_222812530.1 1827496..1828218(-) (mecA) [Streptococcus suis strain NJ3]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMIPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=599952 K6972_RS08960 WP_222812530.1 1827496..1828218(-) (mecA) [Streptococcus suis strain NJ3]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCAGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGATTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471