Detailed information NTG0599952

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: NAT22_RS14380
• Genome accession: NZ_CP098485
• Coordinates: 2994317..2995603 (-)
• Length: 428 a.a.
• NCBI ID: WP_030648610.1
• Uniprot ID: A0A937ED60
• Organism: Streptomyces sp. Caat 7-52
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2989317..3000603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NAT22_RS14365	-	2990031..2992682 (-)	2652	WP_251093366.1	valine--tRNA ligase	-
NAT22_RS14370	-	2992821..2993774 (+)	954	WP_251093367.1	hypothetical protein	-
NAT22_RS14375	-	2993842..2994129 (-)	288	WP_251093368.1	hypothetical protein	-
NAT22_RS14380	clpX	2994317..2995603 (-)	1287	WP_030648610.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
NAT22_RS14385	clpP	2995774..2996439 (-)	666	WP_201815467.1	ATP-dependent Clp protease proteolytic subunit	Regulator
NAT22_RS14390	clpP	2996509..2997114 (-)	606	WP_251096801.1	ATP-dependent Clp protease proteolytic subunit	Regulator
NAT22_RS14395	tig	2997613..2998983 (-)	1371	WP_251093369.1	trigger factor	-

Sequence

Protein

• Length: 428 a.a.
• Molecular weight: 46642.50 Da
• Isoelectric Point: 4.7331

>NTDB_id=599952 NAT22_RS14380 WP_030648610.1 2994317..2995603(-) (clpX) [Streptomyces sp. Caat 7-52]
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEA
AKKALSVAVYNHYKRVQAGENGGASGRDDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGED
VENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQ
IDTTNVLFIVGGAFAGLEKIIEARAGAKGIGFGATILSKRELESKDVFEDVMPEDLVKFGMIPEFIGRLPVITSVHNLDR
EALLKILVEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLQGVMYEVPSRKDVARVVIT
ADVVLSNVNPTLIPRDARGRGSGEQKTA

Nucleotide

• Length: 1287 bp

>NTDB_id=599952 NAT22_RS14380 WP_030648610.1 2994317..2995603(-) (clpX) [Streptomyces sp. Caat 7-52]
GTGGCACGCATCGGTGACGGCGGCGATCTGCTCAAGTGCTCGTTCTGTGGCAAGAGCCAGAAGCAGGTCAAGAAGCTCAT
CGCAGGGCCCGGTGTGTACATCTGCGACGAGTGCATCGATCTCTGCAACGAGATCATCGAGGAGGAACTCGCGGAGACCA
GCGAGGTGCGCTGGGAGGAGCTGCCCAAGCCCCGCGAGATCTACGAGTTCCTCGAGGGCTACGTGGTCGGCCAGGAGGCC
GCAAAGAAGGCCCTCTCCGTCGCGGTGTACAACCACTACAAGCGGGTCCAGGCGGGTGAGAACGGCGGCGCGAGCGGCCG
GGACGACGCGATCGAGCTGGCGAAGTCCAACATCCTGCTGCTCGGCCCCACGGGCTCGGGCAAGACGCTCCTCGCGCAGA
CCCTGGCGCGCATGCTGAACGTCCCGTTCGCGATCGCCGACGCGACGGCGCTGACCGAGGCGGGATACGTCGGCGAGGAC
GTCGAGAACATCCTGCTGAAGCTGATCCAGGCGGCGGACTACGACGTCAAGAAGGCCGAGACCGGGATCATCTACATCGA
CGAGATCGACAAGGTCGCCCGCAAGAGCGAGAACCCGTCGATCACGCGTGACGTCTCCGGCGAGGGCGTGCAGCAGGCCC
TGCTGAAGATCCTGGAGGGCACCACGGCCTCGGTCCCGCCCCAGGGCGGCCGCAAGCACCCCCACCAGGAGTTCATCCAG
ATCGACACGACGAACGTCCTGTTCATCGTGGGCGGCGCCTTCGCGGGCCTGGAGAAGATCATCGAGGCCCGGGCCGGCGC
CAAGGGCATCGGCTTCGGCGCGACGATCCTGTCCAAGCGCGAGCTGGAGTCCAAGGACGTCTTCGAGGACGTCATGCCGG
AGGACCTGGTCAAGTTCGGCATGATCCCCGAGTTCATCGGCCGTCTGCCGGTCATCACCTCGGTCCACAACCTGGACCGC
GAAGCCCTGCTCAAGATCCTGGTGGAGCCCCGCAACGCGCTGGTCAAGCAGTACCAGCGTCTGTTCGAACTCGACGGCGT
GGAGCTGGACTTCGAGCGCGAGGCGCTGGAGGCCATCGCCGACCAGGCCATCCTCCGCCAGACCGGCGCGCGCGGCCTGC
GCGCCATCATGGAGGAGGTCCTCCAGGGCGTGATGTACGAGGTCCCGTCCCGCAAGGACGTCGCCCGCGTCGTCATCACG
GCCGACGTGGTCCTCTCCAACGTCAACCCCACCCTCATCCCGCGGGACGCACGGGGCCGGGGCTCCGGGGAGCAGAAGAC
GGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (115-312)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (318-395)

3D structure

• AlphaFold DB: A0A937ED60

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	63.184	93.925	0.593
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.745	96.028	0.526