Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   K6972_RS03765 Genome accession   NZ_CP082203
Coordinates   731359..733596 (+) Length   745 a.a.
NCBI ID   WP_222812878.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 726359..738596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS03745 (K6972_03745) - 727106..727891 (-) 786 WP_222812873.1 ABC transporter ATP-binding protein -
  K6972_RS03750 (K6972_03750) - 728043..729488 (-) 1446 WP_222812875.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  K6972_RS03755 (K6972_03755) - 729900..730646 (+) 747 WP_024385479.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  K6972_RS03760 (K6972_03760) comEA/celA/cilE 730713..731375 (+) 663 WP_222812876.1 helix-hairpin-helix domain-containing protein Machinery gene
  K6972_RS03765 (K6972_03765) comEC/celB 731359..733596 (+) 2238 WP_222812878.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83888.64 Da        Isoelectric Point: 7.3810

>NTDB_id=599929 K6972_RS03765 WP_222812878.1 731359..733596(+) (comEC/celB) [Streptococcus suis strain NJ3]
MSRSIKLPCQPIHLAVLAVATYFAVHSFSLLTMGLLSLLLVVFGFRQGKAVFLRTLPLLVLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTGLVQLEVEAEVSRPAGQRNFNGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYIKANFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVNKLQIPFSLVYAGLTGFSVSVVRSLVQKVLGNMGLRKLDNFAATVFVCLLML
PRFPLTAGGVLTFTYAFLLTVFDFEDLGQVKKTAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNVFFVFMEKIIVWVADLGFRPWILGKPSGLVLLLLLVSLFMLYDFHRKKNWLLGLSLVLALLFFMTK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSREANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVAVGDRLPIFDSYLEVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIKNYPNLPVDVLKAGHHGSQGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=599929 K6972_RS03765 WP_222812878.1 731359..733596(+) (comEC/celB) [Streptococcus suis strain NJ3]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCTACCTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTCTGCTACTAGTTGTCTTTGGGTTTCGGCAAGGCAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGTTCTGTGTGGTCTCTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGCCCAGTCAGCC
CCGGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATTGACATTAACGGGGACAGCCTGTCCTTTCGGGGTCGGGC
TGATGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAACTGACAGGTTTGG
TCCAGCTAGAAGTGGAAGCAGAAGTCAGCCGGCCAGCTGGTCAGCGGAATTTCAATGGCTTTGACTATCAGGCCTATCTG
AAAACCCAGGGTATCTATCGGACTGTCAAGCTAACAGCGATTAAGAAGATTGTTCCTGTCCAATCTTGGAATGTTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAGCCAATTTTCCTGCTCCCATGAGCCACTATATGACAG
GGCTCTTGTTTGGGGACTTGGACAGCGACTTTGACCAGATGAGCGACCTCTATTCCAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTTTGGGCTTGACCAAGGAAAC
AGTGAATAAATTGCAGATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTGGTGCGGTCCCTGG
TCCAGAAAGTTTTGGGCAATATGGGCTTGCGGAAGCTGGATAATTTTGCGGCGACGGTCTTTGTCTGTCTGCTGATGCTG
CCTCGCTTTCCACTGACAGCAGGAGGAGTGTTGACCTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGACTGCGGTGGAAAGTCTCAGTATTTCGCTGGGGATTCTACCTGTGCTCATGACCTATTTCTATG
CCTTTCAACCCTTGTCTATTCTCCTGACATTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCTTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGTTTTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCAGATTTGGGCTTTCGACCTTGGATACTGGGCAAGCCGTCTGGGCTGGTCCTCTTGCTCCTGCTGGTCAGCCTCTTCA
TGCTCTATGATTTTCACAGGAAGAAAAACTGGCTCCTAGGACTGAGCCTGGTCCTCGCTCTGCTATTTTTCATGACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGATATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGGGTCGATTTTGCAGCCAAGGAAGCTTGGCAGGAGCGGTCTCGGGAGGCAAATGCAG
AGCGGACCTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTGGTCCTGACCCATACCGACGCTGAC
CATGTGGGCGATGTGCTGGAGGTGGCGAAGCAGGTTCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTACC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTCATGTGGTGGCGGTGGGCGACCGCTTGCCGATTTTTGACT
CTTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCTGTTGTCCTTTACGGTCGCTTGTTG
GAAACCAATTTCCTCTTTACAGGGGACTTGGAGCAGGGGGAATTGGACTTGATTAAAAACTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCTGGTCACCATGGCTCCCAAGGCTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TAGTATCTGCTGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAAGAGTGGAGGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.24

99.732

0.541
  comEC/celB Streptococcus mitis NCTC 12261

52.901

99.463

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

52.022

99.597

0.518
  comEC/celB Streptococcus pneumoniae Rx1

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae D39

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae R6

51.752

99.597

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

48.133

100

0.485