Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K6976_RS09225 Genome accession   NZ_CP082202
Coordinates   1908726..1909448 (-) Length   240 a.a.
NCBI ID   WP_074413940.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1903726..1914448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS09205 (K6976_09205) - 1903904..1905127 (-) 1224 WP_222759336.1 cysteine desulfurase -
  K6976_RS09210 (K6976_09210) sufD 1905131..1906393 (-) 1263 WP_222759338.1 Fe-S cluster assembly protein SufD -
  K6976_RS09215 (K6976_09215) sufC 1906410..1907183 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  K6976_RS09220 (K6976_09220) - 1907557..1908729 (-) 1173 WP_024414291.1 glycosyltransferase family 4 protein -
  K6976_RS09225 (K6976_09225) mecA 1908726..1909448 (-) 723 WP_074413940.1 adaptor protein MecA Regulator
  K6976_RS09230 (K6976_09230) - 1909576..1910412 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  K6976_RS09235 (K6976_09235) - 1910538..1912103 (+) 1566 WP_014638629.1 ABC transporter substrate-binding protein/permease -
  K6976_RS09240 (K6976_09240) - 1912096..1912839 (+) 744 WP_105095944.1 amino acid ABC transporter ATP-binding protein -
  K6976_RS09245 (K6976_09245) - 1912964..1913173 (-) 210 WP_009910800.1 hypothetical protein -
  K6976_RS09250 (K6976_09250) - 1913259..1914161 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27987.54 Da        Isoelectric Point: 4.0533

>NTDB_id=599900 K6976_RS09225 WP_074413940.1 1908726..1909448(-) (mecA) [Streptococcus suis strain SS389]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEELFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=599900 K6976_RS09225 WP_074413940.1 1908726..1909448(-) (mecA) [Streptococcus suis strain SS389]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGAGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACAATAGAGGAACTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471