NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	KFZ54_RS02285	Genome accession	NZ_CP098227
Coordinates	478605..479729 (+)	Length	374 a.a.
NCBI ID	WP_032281681.1	Uniprot ID	-
Organism	Escherichia coli strain XJ6-3
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 473605..484729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFZ54_RS02260 (KFZ54_02255)	mscL	473731..474141 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
KFZ54_RS02265 (KFZ54_02260)	trkA	474271..475647 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
KFZ54_RS02270 (KFZ54_02265)	rsmB	475669..476958 (-)	1290	WP_032222877.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KFZ54_RS02275 (KFZ54_02270)	fmt	477004..477951 (-)	948	WP_000004459.1	methionyl-tRNA formyltransferase	-
KFZ54_RS02280 (KFZ54_02275)	def	477966..478475 (-)	510	WP_000114984.1	peptide deformylase	-
KFZ54_RS02285 (KFZ54_02280)	dprA	478605..479729 (+)	1125	WP_032281681.1	DNA-protecting protein DprA	Machinery gene
KFZ54_RS02290 (KFZ54_02285)	smg	479701..480174 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
KFZ54_RS02295 (KFZ54_02290)	yrdD	480203..480745 (+)	543	WP_001129722.1	type I DNA topoisomerase	-
KFZ54_RS02300 (KFZ54_02295)	tsaC	480750..481322 (+)	573	WP_001301437.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
KFZ54_RS02305 (KFZ54_02300)	aroE	481327..482145 (+)	819	WP_032281680.1	shikimate dehydrogenase	-
KFZ54_RS02310 (KFZ54_02305)	yrdB	482142..482399 (+)	258	WP_001070559.1	DUF1488 domain-containing protein	-
KFZ54_RS02315 (KFZ54_02310)	yrdA	482375..482929 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41022.01 Da Isoelectric Point: 6.3845

                                >NTDB_id=598559 KFZ54_RS02285 WP_032281681.1 478605..479729(+) (dprA) [Escherichia coli strain XJ6-3]

MVDTEIWLRLMSVSSLYGDDMVRIAHWVAKQSHIDALVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=598559 KFZ54_RS02285 WP_032281681.1 478605..479729(+) (dprA) [Escherichia coli strain XJ6-3]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG

GGTGGCAAAACAGTCGCATATTGATGCGCTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGAAGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAACGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGTTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.238	98.663	0.476
dprA	Glaesserella parasuis strain SC1401	45.104	90.107	0.406
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.032	82.888	0.406
dprA	Vibrio cholerae strain A1552	49.032	82.888	0.406
dprA	Haemophilus influenzae Rd KW20	43.917	90.107	0.396
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0598559