Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   K5X77_RS07265 Genome accession   NZ_CP081833
Coordinates   1495934..1497190 (-) Length   418 a.a.
NCBI ID   WP_222317030.1    Uniprot ID   -
Organism   Vagococcus lutrae strain BN31     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1490934..1502190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K5X77_RS07245 (K5X77_07245) walK 1491116..1492942 (+) 1827 WP_222317028.1 cell wall metabolism sensor histidine kinase WalK -
  K5X77_RS07250 (K5X77_07250) yycH 1492939..1494243 (+) 1305 WP_126762859.1 two-component system activity regulator YycH -
  K5X77_RS07255 (K5X77_07255) - 1494243..1495073 (+) 831 WP_222317029.1 two-component system regulatory protein YycI -
  K5X77_RS07260 (K5X77_07260) - 1495091..1495897 (+) 807 WP_126762855.1 MBL fold metallo-hydrolase -
  K5X77_RS07265 (K5X77_07265) htrA 1495934..1497190 (-) 1257 WP_222317030.1 trypsin-like peptidase domain-containing protein Regulator
  K5X77_RS07270 (K5X77_07270) rlmH 1497527..1498006 (+) 480 WP_222317031.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  K5X77_RS07275 (K5X77_07275) - 1498366..1498587 (+) 222 WP_222317032.1 hypothetical protein -
  K5X77_RS07280 (K5X77_07280) - 1498664..1498930 (+) 267 WP_222317033.1 JAB domain-containing protein -
  K5X77_RS07285 (K5X77_07285) - 1499049..1500134 (+) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
  K5X77_RS07290 (K5X77_07290) - 1500131..1502023 (+) 1893 WP_001557544.1 site-specific integrase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44306.69 Da        Isoelectric Point: 4.5224

>NTDB_id=597667 K5X77_RS07265 WP_222317030.1 1495934..1497190(-) (htrA) [Vagococcus lutrae strain BN31]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQGSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSENNQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREHH
KNTVKVSLSLDRSSLEKE

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=597667 K5X77_RS07265 WP_222317030.1 1495934..1497190(-) (htrA) [Vagococcus lutrae strain BN31]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGGCAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAAGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTCATTAATTTACAAAAACGACAAGAAATGGCGGATGAATATGGACTTGGTGGATTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAAATAATCAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTACAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGTTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTA
TCCGCTGAACTAGTTGGTGCCGACGCTTATACTGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGTGAACCTGCGATTGCAATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACGATCACGAATCAAAATCCAGAAACAGGCCAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGGCCATTAATTAATATTGCCGGCCAAGTAAT
CGGAATTAACTCCATTAAGATTGCGCGAGCAGCGAGTGGTATCTCTGCTGAGGGGATGGGCTTTTCTATTCCGAGTAATG
ATGTTGTCGATATTATTAATCAACTAGAACAAAACGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTAAAATTACCAACAGATATTAAATCTGGTGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTAGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGTGAGCATCAC
AAAAATACCGTGAAAGTTTCCCTTTCACTCGACCGTTCTTCTTTAGAAAAAGAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(10-408)

Trypsin-like peptidase domain (Trypsin_2)

(123-269)

PDZ domain (PDZ_2)

(312-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

54.331

91.148

0.495
  htrA Streptococcus gordonii str. Challis substr. CH1

48.379

95.933

0.464
  htrA Streptococcus mitis NCTC 12261

49.081

91.148

0.447
  htrA Streptococcus pneumoniae TIGR4

50.139

86.364

0.433
  htrA Streptococcus pneumoniae D39

50.139

86.364

0.433
  htrA Streptococcus pneumoniae Rx1

50.139

86.364

0.433
  htrA Streptococcus pneumoniae R6

50.139

86.364

0.433