Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   K5J94_RS04470 Genome accession   NZ_CP081502
Coordinates   935535..937451 (+) Length   638 a.a.
NCBI ID   WP_159547789.1    Uniprot ID   -
Organism   Streptococcus halichoeri strain Shali_VAS-CPH     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 930535..942451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K5J94_RS04455 fmt 932509..933447 (+) 939 WP_221913656.1 methionyl-tRNA formyltransferase -
  K5J94_RS04460 rsmB 933437..934759 (+) 1323 WP_221913657.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  K5J94_RS04465 - 934798..935538 (+) 741 WP_159547787.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  K5J94_RS04470 pknB 935535..937451 (+) 1917 WP_159547789.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  K5J94_RS04475 liaF 937706..938401 (+) 696 WP_159542789.1 cell wall-active antibiotics response protein LiaF -
  K5J94_RS04480 - 938398..939399 (+) 1002 WP_159547791.1 sensor histidine kinase -
  K5J94_RS04485 - 939396..940037 (+) 642 WP_159542783.1 response regulator transcription factor -
  K5J94_RS04490 - 940071..941471 (+) 1401 WP_159542780.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  K5J94_RS04495 - 941471..941827 (+) 357 WP_159542777.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 638 a.a.        Molecular weight: 69092.31 Da        Isoelectric Point: 9.3576

>NTDB_id=597059 K5J94_RS04470 WP_159547789.1 935535..937451(+) (pknB) [Streptococcus halichoeri strain Shali_VAS-CPH]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVDGADLKKYIQDNAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIGENSQVP
QALENVVIKATAKRLSDRYATTFEMSRDLMTALSYNRSRERKLVFSDTENTKPLPKVTPTPNVAPKATPAPAVKTQSEKT
PQSQPVPKPKKEKKGRFFGTLLKIVFALFIVGLAIFAYLILTKPNAVRVPNVTGSSVAVAREELENLGFKIGKVKEIESN
RVAEGNVVKTDPAAGTSKRQGSKVDLFVSIGNKSFVMKDYKGQQYKDVITELVDTYGVAKSKIKIERIDTNEYEVGTVIG
QSPTSGEKFHPNGKSKITLSVASSDTVSMPVLTGFSYADAVAELTRLGISASRIKGYYPDPNSPTGYTKMASPKGTLVVS
AQDPYAGTKVSVSDTNEISLYFYPSDAAHPDGSSSSDASHNSSQSSSSTSKDATSSSSSSQSSQNGTSHSTSEPTLSP

Nucleotide


Download         Length: 1917 bp        

>NTDB_id=597059 K5J94_RS04470 WP_159547789.1 935535..937451(+) (pknB) [Streptococcus halichoeri strain Shali_VAS-CPH]
ATGATACAGATTGGCAAGCTCTTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGTCGCGGAGGGATGGCTGATGTCTA
TCTAGCTAATGATTTAATCTTAGATAACGAAGATGTAGCCATCAAGGTGTTACGGACGAATTATCAAACCGATCAGGTGG
CAGTTGCTCGTTTCCAACGAGAAGCTCGAGCCATGGCTGAATTGAATCATCCGAACATTGTTGCGATACGAGATATTGGC
GAGGAAGACGGCCAGCAATTCTTAGCAATGGAATATGTGGATGGTGCTGATCTTAAAAAATACATTCAAGATAATGCACC
ACTATCTAATAATGAAGTTGTCCGGATTATGGAAGAAGTCTTGTCAGCTATGACACTGGCTCACCAAAAAGGTATTGTGC
ACCGAGATTTAAAACCGCAAAATATCTTATTAACCAAATCTGGCACGGTTAAGGTTACTGACTTTGGGATTGCAGTAGCT
TTTGCTGAGACCAGTTTAACCCAGACAAATTCCATGCTAGGCAGTGTGCATTATTTATCACCTGAGCAGGCAAGAGGCTC
TAAGGCTACTGTGCAAAGTGATATTTATGCCATGGGGATTATGTTATTTGAAATGTTGACTGGCCATATTCCCTATGATG
GGGACAGTGCCGTTACCATTGCCCTGCAACATTTCCAAAAGCCCCTGCCGTCTATTATTGGAGAAAATAGTCAGGTGCCG
CAGGCTCTGGAAAATGTCGTCATCAAAGCGACAGCTAAACGTTTGTCTGATCGCTATGCGACAACCTTTGAAATGAGTCG
AGACTTGATGACGGCGCTCAGCTATAATCGAAGCCGCGAGCGCAAGCTGGTTTTTAGTGATACTGAAAATACCAAGCCTC
TGCCTAAGGTGACACCGACACCCAATGTAGCACCCAAGGCAACGCCTGCTCCTGCGGTTAAAACACAATCCGAAAAAACG
CCCCAGTCGCAACCAGTGCCAAAGCCAAAAAAAGAAAAGAAGGGCCGCTTTTTTGGCACCCTGCTAAAAATAGTCTTTGC
TCTTTTTATTGTTGGCTTAGCCATCTTTGCCTACTTAATCCTCACTAAGCCTAATGCCGTAAGAGTGCCAAATGTGACCG
GTTCAAGTGTGGCAGTTGCAAGAGAAGAACTGGAAAATCTGGGCTTTAAGATTGGCAAGGTTAAAGAAATAGAAAGTAAC
CGGGTTGCTGAAGGAAATGTTGTCAAAACCGATCCGGCAGCCGGGACCTCCAAACGTCAAGGTTCAAAAGTTGATCTCTT
TGTCTCGATTGGCAACAAAAGCTTTGTGATGAAAGACTACAAGGGCCAGCAGTACAAGGATGTCATCACTGAATTGGTGG
ACACCTACGGCGTTGCAAAATCAAAAATCAAGATTGAACGCATTGATACAAACGAATATGAGGTGGGCACAGTCATCGGC
CAATCGCCAACGAGTGGCGAGAAGTTCCATCCCAATGGTAAATCGAAAATCACCTTGAGTGTGGCCAGTTCTGATACTGT
TTCAATGCCGGTCCTAACAGGCTTTAGCTATGCTGACGCGGTAGCAGAATTGACAAGACTTGGCATTTCTGCCTCCCGGA
TTAAGGGCTATTATCCAGATCCAAATTCTCCAACAGGCTATACCAAAATGGCTTCGCCCAAAGGCACCCTAGTTGTGAGT
GCGCAAGACCCTTATGCTGGTACAAAGGTTAGTGTTTCAGATACTAATGAAATCAGCCTTTACTTCTATCCAAGTGATGC
CGCTCATCCTGATGGCTCATCGTCATCAGATGCTTCGCATAATAGCAGTCAAAGCAGCAGCAGTACTTCAAAAGATGCGA
CATCATCATCGAGCTCCTCACAATCAAGCCAAAATGGGACAAGCCATAGTACATCAGAACCAACCCTGTCACCATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-239)

PASTA domain (PASTA)

(507-583)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(436-502)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

64.906

92.006

0.597
  stkP/pknB Streptococcus salivarius strain HSISS4

62.715

91.223

0.572
  stkP Streptococcus pneumoniae D39

54.992

92.633

0.509
  stkP Streptococcus pneumoniae R6

54.992

92.633

0.509
  stkP Streptococcus pneumoniae TIGR4

54.992

92.633

0.509
  stkP Streptococcus pneumoniae Rx1

54.822

92.633

0.508