Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K5J94_RS04125 Genome accession   NZ_CP081502
Coordinates   851516..852286 (+) Length   256 a.a.
NCBI ID   WP_221913610.1    Uniprot ID   -
Organism   Streptococcus halichoeri strain Shali_VAS-CPH     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 846516..857286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K5J94_RS04105 - 847090..847206 (-) 117 WP_159542978.1 putative metal homeostasis protein -
  K5J94_RS04110 - 847606..848346 (-) 741 WP_159542975.1 amino acid ABC transporter ATP-binding protein -
  K5J94_RS04115 - 848348..849910 (-) 1563 WP_159582996.1 ABC transporter substrate-binding protein/permease -
  K5J94_RS04120 - 850273..851112 (+) 840 WP_159542966.1 undecaprenyl-diphosphate phosphatase -
  K5J94_RS04125 mecA 851516..852286 (+) 771 WP_221913610.1 adaptor protein MecA Regulator
  K5J94_RS04130 - 852291..853466 (+) 1176 WP_221913612.1 glycosyltransferase family 4 protein -
  K5J94_RS09665 - 854120..855334 (+) 1215 WP_408022834.1 LPXTG cell wall anchor domain-containing protein -
  K5J94_RS04140 sufC 855849..856619 (+) 771 WP_159542957.1 Fe-S cluster assembly ATPase SufC -

Sequence

Protein


Download         Length: 256 a.a.        Molecular weight: 29500.11 Da        Isoelectric Point: 4.0149

>NTDB_id=597053 K5J94_RS04125 WP_221913610.1 851516..852286(+) (mecA) [Streptococcus halichoeri strain Shali_VAS-CPH]
MEMKQISETTLKITISMDDLEEREMELKDFLIPQEKTEEFFYSVMDELDLPDTFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLDFEDLADLGDISQMSPEEFFKSLEKSLREKGDTQAHEKLEKLEEAMEDALQDPDASATEQAAMSEGDEEEDVNPLD
YIHYVLVFADLPAVIEFAQAIDFQVEASELYKDNNRYYMTVLLDVQNQPAYYASVMYARLLEHASPTTTTRAYLQEHAPQ
LMVDGALEKLQKVKLV

Nucleotide


Download         Length: 771 bp        

>NTDB_id=597053 K5J94_RS04125 WP_221913610.1 851516..852286(+) (mecA) [Streptococcus halichoeri strain Shali_VAS-CPH]
ATGGAGATGAAACAAATTAGTGAAACAACACTAAAAATTACGATTAGTATGGATGATTTAGAAGAAAGAGAGATGGAATT
AAAGGATTTCTTGATTCCTCAGGAGAAGACCGAAGAGTTCTTTTATTCTGTCATGGATGAGCTAGATCTTCCTGACACTT
TTAAAGATAGTGGCATGTTGAGCTTTAGGGTCACACCGCGCAAAGACCGGCTTGATGTTTTTGTCACCAAATCAGACTTG
AATAAGGACCTTGATTTTGAAGATCTGGCGGACTTGGGTGATATTTCCCAGATGTCTCCTGAGGAGTTTTTCAAATCACT
GGAAAAATCCCTGCGGGAAAAAGGAGATACACAGGCTCATGAAAAGCTTGAAAAACTAGAAGAAGCCATGGAGGATGCCC
TACAAGATCCAGATGCTTCTGCGACAGAGCAAGCTGCCATGAGCGAAGGAGATGAAGAGGAGGATGTTAATCCATTAGAC
TATATTCATTATGTTTTAGTTTTTGCTGATTTGCCTGCCGTTATTGAGTTTGCTCAGGCTATTGATTTTCAGGTGGAAGC
TTCTGAACTTTATAAAGACAACAACCGTTACTATATGACCGTGCTATTGGATGTTCAAAACCAACCAGCTTATTATGCCT
CAGTCATGTATGCTCGCCTGCTGGAACACGCTAGCCCCACGACAACAACGCGAGCTTACTTACAAGAGCATGCTCCCCAA
CTAATGGTAGATGGGGCGCTTGAAAAATTACAAAAGGTAAAATTGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

59.375

100

0.594
  mecA Streptococcus mutans UA159

59.289

98.828

0.586
  mecA Streptococcus thermophilus LMG 18311

58.594

100

0.586
  mecA Streptococcus pneumoniae TIGR4

48.062

100

0.484
  mecA Streptococcus pneumoniae Rx1

48.062

100

0.484
  mecA Streptococcus pneumoniae D39

48.062

100

0.484
  mecA Streptococcus pneumoniae R6

48.062

100

0.484