Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   M9H69_RS00485 Genome accession   NZ_CP097843
Coordinates   73438..74787 (+) Length   449 a.a.
NCBI ID   WP_250315623.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 68438..79787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS00450 (M9H69_00450) - 69261..69497 (+) 237 WP_000136450.1 acyl carrier protein -
  M9H69_RS00455 (M9H69_00455) - 69941..70132 (+) 192 WP_000180812.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  M9H69_RS00460 (M9H69_00460) - 70157..70339 (+) 183 WP_009729537.1 Blp family class II bacteriocin -
  M9H69_RS00465 (M9H69_00465) - 70343..70567 (+) 225 WP_080585587.1 bacteriocin immunity protein -
  M9H69_RS00470 (M9H69_00470) - 70639..70827 (+) 189 WP_195217117.1 hypothetical protein -
  M9H69_RS00475 (M9H69_00475) - 70852..71061 (+) 210 WP_000869800.1 hypothetical protein -
  M9H69_RS00480 (M9H69_00480) comA 71272..73425 (+) 2154 WP_084920041.1 peptide cleavage/export ABC transporter ComA Regulator
  M9H69_RS00485 (M9H69_00485) comB 73438..74787 (+) 1350 WP_250315623.1 competence pheromone export protein ComB Regulator
  M9H69_RS00490 (M9H69_00490) purC 74957..75664 (+) 708 WP_250315624.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  M9H69_RS00495 (M9H69_00495) - 75731..79456 (+) 3726 WP_250315625.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49930.03 Da        Isoelectric Point: 5.5864

>NTDB_id=596559 M9H69_RS00485 WP_250315623.1 73438..74787(+) (comB) [Streptococcus oralis strain HP01]
MQPEFLESAEFYHRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGELLVEYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLTSQNLAYSLYQSYKSQREENPQAKAQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLEKGKITASEDGVLH
LNPETSESTMAAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETHLPPEQAAKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=596559 M9H69_RS00485 WP_250315623.1 73438..74787(+) (comB) [Streptococcus oralis strain HP01]
ATGCAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGAGTGATTTTACCTAT
GTCACTTCTGCTCGTGTTTTTACTTGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCGACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCAACTAGCAATCAACGGATTGTGGCCAACTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGCGAACTACTCGTTGAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTCGAAGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGTTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTGAGGAGCAATGTTTCACAGCAAAAT
GAGACCATCGCGTCCCAGAATGCAGCGGCTAGTCAAACCCAAGCTGAAATCGGGAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCGGCTATTGAAACAGGTGCTTCCTTGACCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTACAAGTCTCAGAGGGAGGAAAATCCGCAAGCTAAGGCTCAGGCTGTTGCACAGGTTGAAGCACAGCTTTCT
CAGTTAGAATCTAGTCTTGCTACTTATCGTGTTCAGTATGCAGGTTCGGGAACCCAGCAAGCCTATGCAACGGGACTGGA
TAGTCAACTGGAATCGCTCAAGTCCCAGCACCTAGTCAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTCCTAGAGAAGGGGAAGATTACAGCAAGCGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGCTGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCTTTGGAAAAAGA
AGGAAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTTAAGATTGGAGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATTTTCCTGGATTCCACTATTACAAGTATTGATGCGACAGCTACAAAGACTGAAAAA
GGAAATTTCTTTAAAATTGAGGCGGAAACCCATCTGCCCCCTGAGCAGGCTGCAAAACTTCGCTATGGCTTAGAAGGCCG
CCTGCAGATGATCACAGGAAAGAAAAGTTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGCTAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(310-423)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

87.277

99.777

0.871
  comB Streptococcus mitis NCTC 12261

85.938

99.777

0.857
  comB Streptococcus pneumoniae D39

85.268

99.777

0.851
  comB Streptococcus pneumoniae R6

85.268

99.777

0.851
  comB Streptococcus pneumoniae Rx1

85.268

99.777

0.851
  comB Streptococcus pneumoniae TIGR4

85.045

99.777

0.849
  comB Streptococcus gordonii str. Challis substr. CH1

54.867

100

0.552