Detailed information NTG0059613

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LOCK900_RS10925
• Genome accession: NC_021723
• Coordinates: 2356986..2359178 (-)
• Length: 730 a.a.
• NCBI ID: WP_005711104.1
• Uniprot ID: -
• Organism: Lacticaseibacillus rhamnosus LOCK900
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2351986..2364178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LOCK900_RS10900 (LOCK900_2351)	-	2352111..2353004 (-)	894	WP_123811849.1	IS3 family transposase	-
LOCK900_RS10905 (LOCK900_2352)	-	2352956..2353492 (-)	537	WP_005714558.1	helix-turn-helix domain-containing protein	-
LOCK900_RS10910 (LOCK900_2353)	-	2353587..2354942 (-)	1356	WP_005711099.1	threonine/serine exporter ThrE family protein	-
LOCK900_RS10915 (LOCK900_2354)	-	2355122..2355475 (-)	354	WP_005714559.1	hypothetical protein	-
LOCK900_RS10920 (LOCK900_2355)	-	2355594..2356973 (-)	1380	WP_005711102.1	bacteriocin secretion accessory protein	-
LOCK900_RS10925 (LOCK900_2356)	comA	2356986..2359178 (-)	2193	WP_005711104.1	peptide cleavage/export ABC transporter	Regulator
LOCK900_RS15040	-	2359473..2359628 (-)	156	WP_005714562.1	bacteriocin-like peptide, LSEI_2386 family	-
LOCK900_RS10930 (LOCK900_2357)	-	2360054..2361103 (+)	1050	WP_225359175.1	GHKL domain-containing protein	-
LOCK900_RS10935 (LOCK900_2358)	-	2361108..2361884 (+)	777	WP_005711110.1	response regulator transcription factor	-
LOCK900_RS10940 (LOCK900_2359)	-	2362003..2362263 (-)	261	WP_005711112.1	hypothetical protein	-
LOCK900_RS10955 (LOCK900_2362)	-	2363238..2363483 (-)	246	WP_005711118.1	hypothetical protein	-
LOCK900_RS10960 (LOCK900_2363)	-	2363733..2364032 (-)	300	WP_005714564.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81512.80 Da
• Isoelectric Point: 7.2454

>NTDB_id=59613 LOCK900_RS10925 WP_005711104.1 2356986..2359178(-) (comA) [Lacticaseibacillus rhamnosus LOCK900]
MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKPVQA
DMQLFDFEDVPYPFIAHVLKRGELLHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLTYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPLRVRDVSFKYGFGQGVLKNVNLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLVAEIAADIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide

• Length: 2193 bp

>NTDB_id=59613 LOCK900_RS10925 WP_005711104.1 2356986..2359178(-) (comA) [Lacticaseibacillus rhamnosus LOCK900]
ATGGTTAAATACACCCCAAAACTAGGCCAGATCACCTACTACAAACGCTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTGGCTGCGTTAAACATGCTGCTTAAATACAATGGGTCGGACTATTCGTTAGCCCACTTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACTGCTTTGGGAATTGTTCGGGCCGCTGAAGCACTAGCGTTTGAGACGAAACCGGTGCAGGCG
GATATGCAGTTGTTTGATTTTGAGGATGTGCCTTATCCGTTTATTGCCCATGTGCTGAAGCGTGGTGAATTGCTTCATTA
TTATGTTGTTTTTAAGGCAACGCGCACGAGTATTCTGATTGGCGATCCTGACCCGTCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCACCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCCATGCTAGCTAAGCAGAAAGGCATCATCGCGAACATTATTCTGGCCGCGGTATT
GATTACGGTCATTAGTATCGTTGGGTCGTATTTTTTGCAGTCTATTATTGATACGTATATACCGAATGCCATGCGGACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCTGTGTTGACTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGACTTGCGATTGATGTCATTTTAGGGTATGTGCGCCATTTATATGAATTGCCGATGTCGTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGACGCGAATAAAATTATTGATGCGCTGGCGAATACGATTA
TGACGTTATTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTATTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAACCAAGAGACGAT
GGAAAGTAACGCAATCTTGAGTTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCCTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACTTATCTGAAGAAATCGTTTAGTTACACTAAGGCAGATCAATTA
CAGCAAGCGATTAAAGGTCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGGGCAAGTTTGGTGATTGCCAA
TCGGATGAGTTTGGGGCAGATGCTGACCTTTAATGCGCTGCTGTCATACTTTACGAATCCGCTTGAAAGCATCATCAACC
TACAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGTTTGAATGAGGTTTATCTGGTTGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGCCCGTTACGCGTTCGGGATGTTTCGTTTAAATATGGTTTTGGCCA
AGGTGTGTTGAAAAACGTCAACCTTGAAGTCCCGGAAAATGCTAAATATACCATCGTCGGCATGAGCGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGCTTTTACCCGGTTGATGCCGATAAAGGAACCATCACGTTTAATGGTATTCCGGTC
AAAGATATTAATCTCACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCATTTATTTTTTCGGGGACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGACTTGACGCAGGCGTGTTTGGTTGCGGAAATTGCTG
CAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAACTGTCAGAAAGCGGCAGCATTTTATCAGGGGGTCAGAAGCAG
CGGCTGGCGATTGCACGAGCCTTGTTATCACCGGCAAAAGTACTCATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACAGAGCGAAAAATTGTCGATCGCTTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACCATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCGACGTTGTTAGCCCAA
GACGGTTATTACGCGCGCCTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (18-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae D39	58.042	97.945	0.568
comA	Streptococcus pneumoniae R6	58.042	97.945	0.568
comA	Streptococcus pneumoniae Rx1	58.042	97.945	0.568
comA	Streptococcus pneumoniae TIGR4	57.622	97.945	0.564
comA	Streptococcus mitis NCTC 12261	57.622	97.945	0.564
comA	Streptococcus mitis SK321	57.483	97.945	0.563
comA	Streptococcus gordonii str. Challis substr. CH1	56.467	98.493	0.556
comA/nlmT	Streptococcus mutans UA159	53.547	98.493	0.527