Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M8286_RS08400 Genome accession   NZ_CP097577
Coordinates   1729035..1729745 (-) Length   236 a.a.
NCBI ID   WP_275600912.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1724035..1734745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS08380 (M8286_08515) - 1724189..1725412 (-) 1224 WP_275600909.1 cysteine desulfurase -
  M8286_RS08385 (M8286_08520) sufD 1725416..1726678 (-) 1263 WP_275600910.1 Fe-S cluster assembly protein SufD -
  M8286_RS08390 (M8286_08525) sufC 1726695..1727468 (-) 774 WP_275600911.1 Fe-S cluster assembly ATPase SufC -
  M8286_RS08395 (M8286_08530) - 1727866..1729038 (-) 1173 WP_358636342.1 MraY family glycosyltransferase -
  M8286_RS08400 (M8286_08540) mecA 1729035..1729745 (-) 711 WP_275600912.1 adaptor protein MecA Regulator
  M8286_RS08405 (M8286_08545) - 1729822..1731315 (-) 1494 WP_358636345.1 IS1182 family transposase -
  M8286_RS08410 (M8286_08550) - 1731440..1732276 (-) 837 WP_208546802.1 undecaprenyl-diphosphate phosphatase -
  M8286_RS08415 (M8286_08555) - 1732403..1733968 (+) 1566 WP_275600913.1 ABC transporter substrate-binding protein/permease -
  M8286_RS08420 (M8286_08560) - 1733961..1734704 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27502.04 Da        Isoelectric Point: 4.0856

>NTDB_id=595747 M8286_RS08400 WP_275600912.1 1729035..1729745(-) (mecA) [Streptococcus suis strain 3112]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEEEADEEEQERYIYYILEFPTIEELFTFVGT
VDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 711 bp        

>NTDB_id=595747 M8286_RS08400 WP_275600912.1 1729035..1729745(-) (mecA) [Streptococcus suis strain 3112]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCGCCAGATGCAACAGCCGTTCGTCATTTGGAAGAGGAAGAAGCAG
ATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGAGCTGTTTACTTTTGTTGGTACG
GTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTATCAATGTAGAAAA
TCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGACCAGACCTGCTT
TACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTATGA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

50.82

100

0.525
  mecA Streptococcus pneumoniae D39

49.59

100

0.513
  mecA Streptococcus pneumoniae R6

49.59

100

0.513
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.513
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.483
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.479