Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   M4R69_RS19945 Genome accession   NZ_CP097198
Coordinates   4123952..4125076 (+) Length   374 a.a.
NCBI ID   WP_096262939.1    Uniprot ID   -
Organism   Escherichia coli strain 2-1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4118952..4130076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M4R69_RS19920 (M4R69_19915) mscL 4119078..4119488 (-) 411 WP_000022439.1 large-conductance mechanosensitive channel protein MscL -
  M4R69_RS19925 (M4R69_19920) trkA 4119618..4120994 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  M4R69_RS19930 (M4R69_19925) rsmB 4121016..4122305 (-) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M4R69_RS19935 (M4R69_19930) fmt 4122351..4123298 (-) 948 WP_000004432.1 methionyl-tRNA formyltransferase -
  M4R69_RS19940 (M4R69_19935) def 4123313..4123822 (-) 510 WP_000114984.1 peptide deformylase -
  M4R69_RS19945 (M4R69_19940) dprA 4123952..4125076 (+) 1125 WP_096262939.1 DNA-protecting protein DprA Machinery gene
  M4R69_RS19950 (M4R69_19945) smg 4125048..4125521 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  M4R69_RS19955 (M4R69_19950) yrdD 4125550..4126092 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  M4R69_RS19960 (M4R69_19955) tsaC 4126097..4126669 (+) 573 WP_001325625.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  M4R69_RS19965 (M4R69_19960) aroE 4126674..4127492 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  M4R69_RS19970 (M4R69_19965) yrdB 4127489..4127746 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  M4R69_RS19975 (M4R69_19970) yrdA 4127722..4128276 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41017.00 Da        Isoelectric Point: 6.3122

>NTDB_id=593963 M4R69_RS19945 WP_096262939.1 4123952..4125076(+) (dprA) [Escherichia coli strain 2-1]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLMTTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKTALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=593963 M4R69_RS19945 WP_096262939.1 4123952..4125076(+) (dprA) [Escherichia coli strain 2-1]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGATGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAACTGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.865

98.93

0.444
  dprA Vibrio cholerae strain A1552

44.865

98.93

0.444
  dprA Glaesserella parasuis strain SC1401

44.838

90.642

0.406
  dprA Haemophilus influenzae Rd KW20

45.104

90.107

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393