Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   M2M89_RS20215 Genome accession   NZ_CP097130
Coordinates   3948036..3950219 (+) Length   727 a.a.
NCBI ID   WP_041850311.1    Uniprot ID   -
Organism   Bacillus subtilis strain S16     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 3943036..3955219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2M89_RS20190 htpG 3943961..3945841 (-) 1881 WP_128442034.1 molecular chaperone HtpG -
  M2M89_RS20195 - 3946009..3946260 (-) 252 WP_003244458.1 hypothetical protein -
  M2M89_RS20200 yxbG 3946377..3947186 (+) 810 WP_041850312.1 SDR family oxidoreductase -
  M2M89_RS20205 - 3947488..3947685 (+) 198 WP_040081241.1 Blp family class II bacteriocin -
  M2M89_RS20210 - 3947709..3947954 (+) 246 WP_040081239.1 Blp family class II bacteriocin -
  M2M89_RS20215 comA/nlmT 3948036..3950219 (+) 2184 WP_041850311.1 peptide cleavage/export ABC transporter Regulator
  M2M89_RS20220 - 3950220..3951689 (+) 1470 WP_128442036.1 HlyD family efflux transporter periplasmic adaptor subunit -
  M2M89_RS20225 yxbF 3952207..3953349 (-) 1143 WP_041850309.1 TetR/AcrR family transcriptional regulator -
  M2M89_RS20230 aldX 3953491..3954828 (+) 1338 WP_128442038.1 aldehyde dehydrogenase family protein -

Sequence

Protein


Download         Length: 727 a.a.        Molecular weight: 82167.07 Da        Isoelectric Point: 8.8892

>NTDB_id=593736 M2M89_RS20215 WP_041850311.1 3948036..3950219(+) (comA/nlmT) [Bacillus subtilis strain S16]
MFFKKYQYVKQIDEKDCGAACLATILKHYGSKLSINKIRDIAGTDKQGTSALGLVRAAEQLGFSAKGVKADKTALEEPFT
LPAIAHIILNGQLLHYVVIHKITKDQIIIADPGRGIIKYTKKEFLEVWTGILILLTPSETYKIHVETSTIRSDIFKLILH
QKSLIIHTILASFIITVFGIMGTFYFQTVIDEILPNRLNSTLHILSFGLIIMYLFKVLLTAFRQYLMILLGQKLSISIMF
GYFKHVLSLPMKFFSTRKIGEIISRFNDASKVIDAIISASLSVVLDTVMLVMVGIFLYLQNTTLFLITLAFIPFYVLTVW
FFMKPYESINNTEMENNAQLTSKIVETLNGIETIKAYNAEYMMSYETEKRFVKYLRSAFKHGVIDNLQNSIKMFLDLASG
AFILWIGSTQVMKGTLSIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEILEVEHEIKDKDAQITTPGSING
PIEFIKINFRYGTRRLILKDITLRIDKGEKVAFIGESGSGKSTLTKLLMKFYTAESGDILINGYHINDIHAHSLRESISY
IPQESHFIQGSIFENLLLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALLRKPNI
LIMDESTSNLDTTTEQGISKMIYDQTVGITTIIIAHRLSTIMNCDKIFVMENGEIIEYGNHNDLLKKKGKYYELWENQMP
SRGMVTI

Nucleotide


Download         Length: 2184 bp        

>NTDB_id=593736 M2M89_RS20215 WP_041850311.1 3948036..3950219(+) (comA/nlmT) [Bacillus subtilis strain S16]
ATGTTCTTTAAAAAGTACCAATATGTAAAACAAATTGATGAAAAAGACTGTGGAGCAGCTTGTCTAGCCACTATATTGAA
GCATTACGGCTCCAAATTATCAATAAATAAAATTCGAGATATTGCGGGAACAGATAAACAAGGCACAAGCGCACTTGGAC
TAGTCAGAGCAGCTGAACAATTAGGCTTTTCAGCAAAAGGAGTAAAAGCTGACAAAACAGCTTTAGAAGAACCCTTTACA
CTGCCGGCTATTGCACATATCATTCTTAATGGACAATTATTACATTATGTTGTTATTCATAAAATTACAAAAGACCAGAT
TATCATTGCAGATCCTGGCCGCGGAATCATTAAGTACACAAAAAAAGAATTTTTAGAGGTTTGGACAGGAATCTTAATTT
TACTGACTCCTTCTGAAACATATAAGATCCATGTAGAGACCAGTACTATACGAAGTGATATATTCAAATTAATACTTCAT
CAAAAATCATTGATCATCCACACAATTTTAGCATCCTTTATCATTACAGTTTTCGGTATTATGGGGACTTTTTATTTTCA
AACGGTCATTGATGAGATTTTACCAAATAGATTGAATAGCACGTTACATATACTTTCATTCGGCCTCATCATTATGTACT
TATTTAAAGTCCTTTTAACAGCCTTTAGGCAATATTTAATGATATTATTGGGCCAAAAATTAAGTATTTCAATAATGTTT
GGTTATTTCAAACATGTACTTAGCTTACCGATGAAGTTTTTTAGCACTAGAAAGATCGGGGAGATTATATCTAGATTTAA
TGATGCTAGCAAAGTAATTGATGCTATTATTAGCGCCTCTCTATCAGTAGTACTTGATACAGTAATGCTTGTAATGGTAG
GCATCTTTTTATATCTACAAAATACAACTTTATTTTTAATTACATTGGCTTTTATCCCATTTTATGTTCTTACAGTTTGG
TTTTTTATGAAGCCATATGAATCCATCAACAATACTGAAATGGAAAACAATGCTCAGCTGACTTCAAAAATAGTTGAGAC
ACTTAACGGTATTGAAACAATTAAAGCATATAATGCTGAATATATGATGTCATATGAGACAGAAAAGAGATTTGTGAAAT
ATTTGCGCTCTGCTTTTAAGCATGGAGTTATCGATAATCTTCAAAATTCTATTAAAATGTTTTTGGATTTAGCAAGTGGA
GCATTCATATTGTGGATTGGTTCAACTCAAGTGATGAAAGGAACTCTTTCAATAGGTCAGCTCATTACATACAATGCATT
GTTAACATATTTTTTGAATCCTTTACAGAACATAATAGGCCTTCAATCGAAACTCCAGTCAGCTTCTGTTGCTTCTAAAC
GACTGGGAGAAATACTAGAAGTAGAACACGAAATAAAAGATAAGGATGCTCAAATAACAACGCCAGGGTCTATTAATGGC
CCAATTGAATTTATTAAAATTAACTTTCGATATGGTACTCGGCGACTAATCCTAAAAGATATTACACTACGTATAGATAA
AGGGGAGAAAGTCGCTTTTATTGGAGAGAGCGGTTCCGGAAAATCTACTCTAACTAAGCTCTTAATGAAATTTTATACAG
CTGAGTCTGGTGATATTTTAATTAATGGTTATCATATCAATGATATTCATGCTCATTCATTAAGAGAAAGTATAAGTTAT
ATCCCTCAAGAATCTCACTTTATACAGGGTTCCATTTTTGAAAACCTTCTGCTCGGTAACTCAGGCAGTTTTACCTTTGA
AGAGATTATAGAAGTATGCAAACAAACAAATGTACACGATTTTGTCAATGATTTACCAATGAGATACGATACTCTCGTAG
AGGAAAACGGGTCTAATTTATCTGGAGGCCAGAAGCAAAGACTCGCAATTGCCAGAGCATTATTAAGAAAACCTAACATT
CTCATAATGGATGAATCAACAAGCAATCTCGATACGACTACCGAACAGGGAATATCAAAAATGATATACGATCAGACTGT
TGGTATAACTACGATTATAATCGCTCACCGTTTGAGTACAATTATGAATTGTGACAAAATATTTGTCATGGAAAATGGAG
AAATCATAGAGTATGGGAACCACAATGATTTATTGAAGAAAAAAGGCAAGTACTATGAGTTGTGGGAGAACCAAATGCCA
TCCAGAGGGATGGTGACTATTTAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(498-648)

Peptidase C39 family (Peptidase_C39)

(5-139)

ABC transporter transmembrane region (ABC_membrane)

(168-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

42.42

98.9

0.42
  comA Streptococcus mitis SK321

41.864

98.9

0.414
  comA Streptococcus mitis NCTC 12261

41.864

98.9

0.414
  comA Streptococcus pneumoniae R6

41.725

98.9

0.413
  comA Streptococcus pneumoniae Rx1

41.725

98.9

0.413
  comA Streptococcus gordonii str. Challis substr. CH1

41.725

98.9

0.413
  comA Streptococcus pneumoniae D39

41.725

98.9

0.413
  comA Streptococcus pneumoniae TIGR4

41.586

98.9

0.411