NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	MYF74_RS02300	Genome accession	NZ_CP096837
Coordinates	487671..488795 (+)	Length	374 a.a.
NCBI ID	WP_000228557.1	Uniprot ID	-
Organism	Escherichia coli strain PS10-3
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 482671..493795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MYF74_RS02275 (MYF74_02275)	mscL	482797..483207 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
MYF74_RS02280 (MYF74_02280)	trkA	483337..484713 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
MYF74_RS02285 (MYF74_02285)	rsmB	484735..486024 (-)	1290	WP_001308089.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
MYF74_RS02290 (MYF74_02290)	fmt	486070..487017 (-)	948	WP_000004458.1	methionyl-tRNA formyltransferase	-
MYF74_RS02295 (MYF74_02295)	def	487032..487541 (-)	510	WP_000114984.1	peptide deformylase	-
MYF74_RS02300 (MYF74_02300)	dprA	487671..488795 (+)	1125	WP_000228557.1	DNA-protecting protein DprA	Machinery gene
MYF74_RS02305 (MYF74_02305)	smg	488767..489240 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
MYF74_RS02310 (MYF74_02310)	yrdD	489269..489811 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
MYF74_RS02315 (MYF74_02315)	tsaC	489816..490388 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
MYF74_RS02320 (MYF74_02320)	aroE	490393..491211 (+)	819	WP_000451252.1	shikimate dehydrogenase	-
MYF74_RS02325 (MYF74_02325)	yrdB	491208..491465 (+)	258	WP_001070591.1	DUF1488 domain-containing protein	-
MYF74_RS02330 (MYF74_02330)	yrdA	491441..491995 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41006.93 Da Isoelectric Point: 6.2662

                                >NTDB_id=590930 MYF74_RS02300 WP_000228557.1 487671..488795(+) (dprA) [Escherichia coli strain PS10-3]

MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTVRCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=590930 MYF74_RS02300 WP_000228557.1 487671..488795(+) (dprA) [Escherichia coli strain PS10-3]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG

GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCACGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGTACGTTGTGCG

CTTGAGCAGGGGCGCGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	47.967	98.663	0.473
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.387	82.888	0.401
dprA	Vibrio cholerae strain A1552	48.387	82.888	0.401
dprA	Glaesserella parasuis strain SC1401	44.51	90.107	0.401
dprA	Legionella pneumophila strain ERS1305867	43.068	90.642	0.39
dprA	Haemophilus influenzae Rd KW20	43.323	90.107	0.39

Detailed information NTG0590930