Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LPB404_RS02710 Genome accession   NZ_CP079821
Coordinates   531804..532550 (+) Length   248 a.a.
NCBI ID   WP_219074976.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 526804..537550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS02695 (LPB404_02695) - 526904..528466 (-) 1563 WP_219074973.1 ABC transporter substrate-binding protein/permease -
  LPB404_RS02700 (LPB404_02700) - 528586..530493 (+) 1908 WP_219074974.1 DUF2207 domain-containing protein -
  LPB404_RS02705 (LPB404_02705) - 530803..531639 (+) 837 WP_219074975.1 undecaprenyl-diphosphate phosphatase -
  LPB404_RS02710 (LPB404_02710) mecA 531804..532550 (+) 747 WP_219074976.1 adaptor protein MecA Regulator
  LPB404_RS02715 (LPB404_02715) - 532547..533704 (+) 1158 WP_219074977.1 glycosyltransferase family 4 protein -
  LPB404_RS02720 (LPB404_02720) sufC 533791..534561 (+) 771 WP_023022208.1 Fe-S cluster assembly ATPase SufC -
  LPB404_RS02725 (LPB404_02725) sufD 534603..535865 (+) 1263 WP_219074978.1 Fe-S cluster assembly protein SufD -
  LPB404_RS02730 (LPB404_02730) - 535868..537094 (+) 1227 WP_219074979.1 cysteine desulfurase -
  LPB404_RS02735 (LPB404_02735) sufU 537081..537515 (+) 435 WP_219074980.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28868.56 Da        Isoelectric Point: 4.0910

>NTDB_id=589740 LPB404_RS02710 WP_219074976.1 531804..532550(+) (mecA) [Streptococcus rubneri strain LPB0404]
MKMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQHLNFEDFSDLPDMEELSQMSPDEFIKTLEKTISEKSKGDGDAIRHLEAEELADENQLSEEETPNHPVDTRYIYYILQF
SQLEEVIRFTKTVHYAVETSELYKMDGMYYLTILIDLEGCPQDYPGWLLATMREYAEDTDTTRAVLQEHGHLLLVSDAIH
ELQKVNLV

Nucleotide


Download         Length: 747 bp        

>NTDB_id=589740 LPB404_RS02710 WP_219074976.1 531804..532550(+) (mecA) [Streptococcus rubneri strain LPB0404]
ATGAAGATGAAGCAAATCAGTGATTCAACCATTAAAATCACGATTCAATTAGAGGACTTAGAAGAACGGGGCATGGAAAT
GGCCGATTTTTTGGTGCCTCAAGAAAAAACAGAAGAATTTTTCTATACCATCTTAGATGAATTAGAAATGCCAGAAAGTT
TCTTAGACAGTGGTATGTTAAGTTTTCGAGTGACCCCTAAGCCAGATAAACTCGATGTTTTTGTGACCAAATCAAAAATT
GATCAGCATTTAAATTTTGAAGATTTTTCCGACTTGCCTGATATGGAAGAATTGTCGCAAATGTCTCCGGACGAATTTAT
CAAAACCTTGGAAAAAACCATCTCTGAAAAGAGTAAGGGAGACGGCGATGCGATCCGTCATTTAGAAGCTGAGGAATTGG
CTGACGAAAATCAGCTTTCAGAAGAAGAAACACCTAATCATCCAGTAGATACACGGTATATTTATTATATCCTCCAGTTT
TCTCAGTTGGAAGAAGTGATTCGGTTTACAAAGACAGTTCATTATGCTGTTGAGACTTCTGAACTTTATAAAATGGACGG
GATGTACTATTTAACCATCCTGATCGATTTGGAAGGGTGTCCGCAAGATTATCCAGGTTGGCTCTTGGCAACCATGCGTG
AATATGCGGAAGATACAGATACTACTAGAGCTGTCCTTCAGGAACATGGCCATCTCTTGCTCGTCTCAGATGCTATTCAC
GAACTTCAAAAGGTTAATTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.26

99.194

0.657
  mecA Streptococcus pneumoniae D39

66.26

99.194

0.657
  mecA Streptococcus pneumoniae R6

66.26

99.194

0.657
  mecA Streptococcus pneumoniae TIGR4

66.26

99.194

0.657
  mecA Streptococcus mutans UA159

50.8

100

0.512
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.468
  mecA Streptococcus thermophilus LMG 18311

46.185

100

0.464