Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   KX728_RS07285 Genome accession   NZ_CP079724
Coordinates   1481818..1483716 (-) Length   632 a.a.
NCBI ID   WP_219108621.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1476818..1488716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS07260 (KX728_07255) - 1476833..1477798 (+) 966 WP_215804400.1 LacI family DNA-binding transcriptional regulator -
  KX728_RS07265 (KX728_07260) - 1477950..1479224 (-) 1275 WP_215804399.1 hydroxymethylglutaryl-CoA reductase, degradative -
  KX728_RS07270 (KX728_07265) - 1479224..1480396 (-) 1173 WP_215804950.1 hydroxymethylglutaryl-CoA synthase -
  KX728_RS07275 (KX728_07270) - 1480515..1480970 (-) 456 WP_000176909.1 threonine/serine exporter family protein -
  KX728_RS07280 (KX728_07275) - 1480972..1481730 (-) 759 WP_070657751.1 threonine/serine exporter family protein -
  KX728_RS07285 (KX728_07280) stkP 1481818..1483716 (-) 1899 WP_219108621.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KX728_RS07290 (KX728_07285) - 1483713..1484453 (-) 741 WP_215804397.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KX728_RS07295 (KX728_07290) rsmB 1484469..1485782 (-) 1314 WP_215804396.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KX728_RS07300 (KX728_07295) fmt 1485775..1486710 (-) 936 WP_215804395.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 68850.18 Da        Isoelectric Point: 8.9647

>NTDB_id=588990 KX728_RS07285 WP_219108621.1 1481818..1483716(-) (stkP) [Streptococcus oralis strain 34]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPVPAPKPAKKRKFKARYMILLASLLLVAASLIWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTI
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTPEGTKEGTVVDQTPK
AGELVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGNTPSSSSSNNEGSHESSRD

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=588990 KX728_RS07285 WP_219108621.1 1481818..1483716(-) (stkP) [Streptococcus oralis strain 34]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTTGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGCCTTGACCTCAAGCGTTATATTAAAGAACACTATCC
TCTTTCAAATGAAGAAGCGGTTCGGATCATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCAGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCCGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACCAACTCAATGTTAGGCTCCGTTCATTATTTGTCACCTGAACAAGCGCGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGCGCGGTTACGATTGCCCTCCAGCATTTCCAGAAACCACTTCCGTCCGTCATAGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCGACTGCTAAGAAGCTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCACCTGCGCAGGAAGAACGCCCTCAGCCAAAG
AAACCGACTCAACCAGTGGCAGAACCGGTTCCAGCGCCAAAGCCAGCTAAGAAACGGAAATTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCGGCCTCTTTAATCTGGATTTTGTCTAGAACACCTGCAACGATTCCCATTCCTG
ATGTGGCTGGACAAACCGTTGCAGAGGCCAAAGAAGCACTCAAAAAATCCAAGTTTGAAGCTGGTGAAGAGAAATCGGAG
GCTAGCGATACAGTAGCGGAAGGACGCGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGGAAGCAATCTTTCCAATTGAGCAATTACGTCGGACGTAAGTATACGGATGTTGTAGCCG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGTGAACCTGGAACCATC
CTTAGACAGACTCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCTACTACGATTACCTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCTAGCTACATCGGCTCAAGTCTTGAATTTACTAAGAATAATCTGACTCAGATTGTCGGTGTAA
AAGAGGCTAATATCGAAGTTGTTGAAGTATCGACTCCTGAAGGAACAAAAGAGGGCACGGTTGTAGATCAAACGCCAAAA
GCAGGAGAACTGGTTGATCTTGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTCATC
CTCTAATCCTGCCCAACGTGGGAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAGGGA
ACACTCCTTCGAGCAGTTCATCCAATAATGAAGGTTCTCACGAAAGTTCGCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(372-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

92.722

0.729
  stkP Streptococcus pneumoniae D39

78.328

92.722

0.726
  stkP Streptococcus pneumoniae R6

78.328

92.722

0.726
  stkP Streptococcus pneumoniae Rx1

78.157

92.722

0.725
  pknB Streptococcus mutans UA159

56.153

91.297

0.513
  stkP/pknB Streptococcus salivarius strain HSISS4

53.584

92.722

0.497