NTDB

Overview

Name	dprA/cilB/dalA	Type	Machinery gene
Locus tag	KX728_RS04190	Genome accession	NZ_CP079724
Coordinates	834143..834991 (+)	Length	282 a.a.
NCBI ID	WP_215804725.1	Uniprot ID	-
Organism	Streptococcus oralis strain 34
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 829143..839991

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS04175 (KX728_04170)	-	830663..831391 (+)	729	WP_215804728.1	metallophosphoesterase family protein	-
KX728_RS04180 (KX728_04175)	lepA	831470..833293 (+)	1824	WP_215804727.1	translation elongation factor 4	-
KX728_RS04185 (KX728_04180)	-	833438..834061 (+)	624	WP_215804726.1	hypothetical protein	-
KX728_RS04190 (KX728_04185)	dprA/cilB/dalA	834143..834991 (+)	849	WP_215804725.1	DNA-processing protein DprA	Machinery gene
KX728_RS04195 (KX728_04190)	topA	835109..837196 (+)	2088	WP_215804724.1	type I DNA topoisomerase	-
KX728_RS04200 (KX728_04195)	-	837303..837662 (+)	360	WP_215804723.1	YbaN family protein	-
KX728_RS04205 (KX728_04200)	-	837756..838388 (+)	633	WP_215804722.1	copper homeostasis protein CutC	-
KX728_RS04210 (KX728_04205)	-	838432..839088 (+)	657	WP_215804721.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

Download Length: 282 a.a. Molecular weight: 31313.85 Da Isoelectric Point: 5.2070

                                >NTDB_id=588974 KX728_RS04190 WP_215804725.1 834143..834991(+) (dprA/cilB/dalA) [Streptococcus oralis strain 34]

MKITNYEIYKLRKAGLTNQQILTVLEYDETVEQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC

YPWDLSEIYDPPALLFYKGNLDLLKFPKVALVGSRSCSSQGAKSIQKIIQGLENELIVVSGLAKGIDTAAHMAALQNGGR

TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE

GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide

Download Length: 849 bp

                                >NTDB_id=588974 KX728_RS04190 WP_215804725.1 834143..834991(+) (dprA/cilB/dalA) [Streptococcus oralis strain 34]

ATGAAAATCACAAATTATGAGATTTACAAATTAAGAAAAGCAGGTTTGACCAATCAACAGATTTTAACTGTCCTTGAATA

TGACGAAACTGTGGAGCAGGAACTTTTGTTAGGAGATATTGCTGAAATCTCTGGTTGTCGCAATCCTGCTGTCTTTATGG

AACGCTATTTCCAGATTGATGATGCGCAGTTGGAGAAGGAGTTTCAAAAATTTCCATCCTTCTCGATTCTAGACGACTGT

TATCCTTGGGATCTGAGTGAGATTTATGACCCTCCAGCTCTTTTGTTTTACAAAGGGAATCTGGACTTATTGAAATTTCC

CAAGGTTGCTCTTGTAGGGAGCCGTTCTTGTTCGAGCCAAGGTGCTAAGTCAATCCAGAAAATTATCCAAGGTTTAGAAA

ACGAGTTAATCGTGGTTAGTGGTTTAGCCAAAGGGATTGATACGGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA

ACAATTGCTGTCATTGGAACAGGATTGGATGTTTTCTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA

CCATTTGGTACTTAGCGAGTATGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGCATCATTGCTG

GCCTTTGCCGTGGTGTGATTGTAGCAGAAGCAAGGATGCGTTCTGGTAGTCTTATCACCTGTGAGCGAGCTATGGAGGAA

GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC

AAAGCTGATTAGCAGTGGTCAAGATGTGTTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	89.716	100	0.897
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	89.362	100	0.894
dprA/cilB/dalA	Streptococcus pneumoniae D39	89.362	100	0.894
dprA/cilB/dalA	Streptococcus pneumoniae R6	89.362	100	0.894
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	89.362	100	0.894
dprA/cilB/dalA	Streptococcus mitis SK321	89.362	100	0.894
dprA	Streptococcus mutans UA159	60.714	99.291	0.603
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.291	0.543

Detailed information NTG0588974