Detailed information NTG0588177

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: KWY62_RS10220
• Genome accession: NZ_CP079193
• Coordinates: 2125992..2127188 (+)
• Length: 398 a.a.
• NCBI ID: WP_044679209.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ID41570
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2120992..2132188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KWY62_RS10190 (KWY62_10190)	-	2121651..2124230 (+)	2580	WP_044679302.1	YfhO family protein	-
KWY62_RS10210 (KWY62_10210)	-	2124631..2125314 (-)	684	WP_024379536.1	YoaK family protein	-
KWY62_RS10215 (KWY62_10215)	rlmH	2125339..2125818 (-)	480	WP_023371894.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
KWY62_RS10220 (KWY62_10220)	htrA	2125992..2127188 (+)	1197	WP_044679209.1	S1C family serine protease	Regulator
KWY62_RS10225 (KWY62_10225)	spo0J	2127249..2128013 (+)	765	WP_024402081.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41852.90 Da
• Isoelectric Point: 4.5454

>NTDB_id=588177 KWY62_RS10220 WP_044679209.1 2125992..2127188(+) (htrA) [Streptococcus suis strain ID41570]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSTITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=588177 KWY62_RS10220 WP_044679209.1 2125992..2127188(+) (htrA) [Streptococcus suis strain ID41570]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTACTATCACTAGTGTCAGCAATGTTCAATACA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCTAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ATGGTCAAACAATCTCAACCAACGCTATTCAAACCGATACAGCTATCAACCCTGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTAGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGATCTCCAAAGCGCTCTCTACAAACATCAGATTGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTAACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.453	99.749	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	60.506	99.246	0.6
htrA	Streptococcus pneumoniae Rx1	57.506	98.744	0.568
htrA	Streptococcus pneumoniae D39	57.506	98.744	0.568
htrA	Streptococcus pneumoniae R6	57.506	98.744	0.568
htrA	Streptococcus pneumoniae TIGR4	57.506	98.744	0.568
htrA	Streptococcus mitis NCTC 12261	57.506	98.744	0.568