Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   KWY62_RS07120 Genome accession   NZ_CP079193
Coordinates   1446319..1447023 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain ID41570     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1441319..1452023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KWY62_RS07105 (KWY62_07105) vga(F) 1442289..1443674 (-) 1386 WP_202847633.1 ABC-F type ribosomal protection protein Vga(F) -
  KWY62_RS07110 (KWY62_07110) vicX 1444167..1444970 (-) 804 WP_024407014.1 MBL fold metallo-hydrolase Regulator
  KWY62_RS07115 (KWY62_07115) micB 1444977..1446326 (-) 1350 WP_029180103.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KWY62_RS07120 (KWY62_07120) micA 1446319..1447023 (-) 705 WP_002935840.1 response regulator YycF Regulator
  KWY62_RS07125 (KWY62_07125) - 1447217..1447978 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  KWY62_RS07130 (KWY62_07130) - 1447989..1448828 (+) 840 WP_202847632.1 transporter substrate-binding domain-containing protein -
  KWY62_RS07135 (KWY62_07135) - 1448843..1449541 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  KWY62_RS07140 (KWY62_07140) - 1449556..1450215 (+) 660 WP_014637676.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=588163 KWY62_RS07120 WP_002935840.1 1446319..1447023(-) (micA) [Streptococcus suis strain ID41570]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=588163 KWY62_RS07120 WP_002935840.1 1446319..1447023(-) (micA) [Streptococcus suis strain ID41570]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGGTATGA
AGTTGTGACAGCTTTTGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376