Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   TL13_RS00330 Genome accession   NC_021213
Coordinates   56623..57522 (+) Length   299 a.a.
NCBI ID   WP_015646238.1    Uniprot ID   -
Organism   Streptococcus suis TL13     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 51623..62522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS00310 (TL13_0063) - 51827..52597 (+) 771 WP_041179355.1 membrane protein -
  TL13_RS11015 (TL13_0064) - 52600..54304 (+) 1705 Protein_43 ABC transporter ATP-binding protein -
  TL13_RS10745 (TL13_0065) - 54405..54578 (+) 174 WP_015646236.1 hypothetical protein -
  TL13_RS00320 (TL13_0066) ruvB 54826..55827 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  TL13_RS00325 (TL13_0067) - 55895..56518 (+) 624 WP_015646237.1 HAD-IA family hydrolase -
  TL13_RS00330 (TL13_0068) comR 56623..57522 (+) 900 WP_015646238.1 helix-turn-helix domain-containing protein Regulator
  TL13_RS00335 (TL13_0069) - 57729..58949 (+) 1221 WP_015646239.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  TL13_RS00345 (TL13_0071) - 59140..60663 (+) 1524 WP_015646241.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35175.03 Da        Isoelectric Point: 4.5398

>NTDB_id=58600 TL13_RS00330 WP_015646238.1 56623..57522(+) (comR) [Streptococcus suis TL13]
MNDKEFGQRVRQLRENASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEQKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=58600 TL13_RS00330 WP_015646238.1 56623..57522(+) (comR) [Streptococcus suis TL13]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAAACGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAACTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTACCCGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTCAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGTGTGTTGAAATGGAAGTATGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGCAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

92.977

100

0.93
  comR Streptococcus suis 05ZYH33

92.977

100

0.93
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

45.151

100

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

97.324

0.368
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368

Multiple sequence alignment