Detailed information NTG0585678

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: KVP03_RS09725
• Genome accession: NZ_CP077959
• Coordinates: 2045547..2047442 (-)
• Length: 631 a.a.
• NCBI ID: WP_012516145.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_14-145
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 2040547..2052442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVP03_RS09700 (KVP03_09680)	-	2041292..2041654 (-)	363	WP_111692702.1	S1 RNA-binding domain-containing protein	-
KVP03_RS09705 (KVP03_09685)	-	2041654..2043054 (-)	1401	WP_111692703.1	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	-
KVP03_RS09710 (KVP03_09690)	-	2043087..2043728 (-)	642	WP_041785672.1	response regulator transcription factor	-
KVP03_RS09715 (KVP03_09695)	-	2043721..2044725 (-)	1005	WP_012516143.1	sensor histidine kinase	-
KVP03_RS09720 (KVP03_09700)	liaF	2044722..2045414 (-)	693	WP_012679994.1	cell wall-active antibiotics response protein LiaF	-
KVP03_RS09725 (KVP03_09705)	pknB	2045547..2047442 (-)	1896	WP_012516145.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
KVP03_RS09730 (KVP03_09710)	-	2047439..2048179 (-)	741	WP_012516146.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
KVP03_RS09735 (KVP03_09715)	rsmB	2048217..2049539 (-)	1323	WP_154299222.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KVP03_RS09740 (KVP03_09720)	fmt	2049529..2050464 (-)	936	WP_230923094.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 631 a.a.
• Molecular weight: 68570.71 Da
• Isoelectric Point: 6.6073

>NTDB_id=585678 KVP03_RS09725 WP_012516145.1 2045547..2047442(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADAR
LEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSS
KAVVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSSPNPSAGDTTDSSSHTELGQNDAVTTP

Nucleotide

• Length: 1896 bp

>NTDB_id=585678 KVP03_RS09725 WP_012516145.1 2045547..2047442(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCTAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACGATTCAAAGTGATATTTACGCGATGGGAATTATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTTTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAGAACGTCGTTATTCGGGCTACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGATTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTGTCTTTGATGATGTCGAAAGCACAAAGCCCT
TGCCAAAGGTAACACCGACTCCTGTAACAGCACCTAAGGTATCAAATGCTAGTCAGGCATCTGCGGCAGCTGATGCTAGA
CTTGAGCAGACTAGCCAGATGGATACTCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGTTTTCTAGGAACACTCTT
AAAAATCTTGTTTTCCTTTTTTGTTGTTGGTGTGGCTCTTTTTGCTTATTTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCGGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGTGACACAGTTAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTACCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAAGATGTGA
TGACCAGTCTGACTGAGACCTATGGTGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATATCCTGAA
AACACCGTTATTAGCCAGTCTCCAAGCGCGGGAGAAAAATTTAACCCAGCTGGTAAATCTAAGATTACCCTTAGTGTAGC
AGTGGGTGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGATGCAGTCAATACACTAACAGCTTTAGGAA
TTGATGCCGCAAGAATCAAGGCCTATGTACCAAGCTCCAGCTCTCCGACAGGCTTTGTGCAGGTGAGCTCCCCAAGCTCA
AAGGCGGTTGTCAGTGGGCAAACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGCAGCTCATCGAGCTCTGATACCTCATCTCCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTACAACACCGTAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (372-434)

• PASTA domain (PASTA) (512-588)

• PASTA domain (PASTA) (441-506)

• Protein kinase domain (Pkinase) (12-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	65.714	94.295	0.62
stkP/pknB	Streptococcus salivarius strain HSISS4	62.245	93.185	0.58
stkP	Streptococcus pneumoniae TIGR4	57.558	81.775	0.471
stkP	Streptococcus pneumoniae D39	57.171	81.775	0.468
stkP	Streptococcus pneumoniae R6	57.171	81.775	0.468
stkP	Streptococcus pneumoniae Rx1	56.977	81.775	0.466