Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU514_RS12755 Genome accession   NZ_CP077919
Coordinates   2562008..2562724 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 278     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2557008..2567724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU514_RS12735 (KU514_12660) - 2558100..2559050 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  KU514_RS12740 (KU514_12665) - 2559199..2560683 (+) 1485 WP_000141411.1 sucrose-6-phosphate hydrolase -
  KU514_RS12745 (KU514_12670) - 2560680..2561639 (+) 960 WP_001253291.1 carbohydrate kinase -
  KU514_RS12750 (KU514_12675) - 2561827..2561936 (-) 110 Protein_2447 hypothetical protein -
  KU514_RS12755 (KU514_12680) agrA 2562008..2562724 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  KU514_RS12760 (KU514_12685) - 2562743..2564026 (-) 1284 WP_047928561.1 sensor histidine kinase -
  KU514_RS12765 (KU514_12690) - 2564056..2564199 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  KU514_RS12770 (KU514_12695) - 2564202..2564765 (-) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  KU514_RS12775 hld 2565055..2565135 (+) 81 WP_000046022.1 delta-hemolysin -
  KU514_RS12780 (KU514_12705) - 2565735..2566520 (-) 786 WP_000867950.1 carbon-nitrogen family hydrolase -
  KU514_RS12785 (KU514_12710) - 2566881..2567507 (-) 627 WP_225806585.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=585099 KU514_RS12755 WP_000688498.1 2562008..2562724(-) (agrA) [Staphylococcus aureus strain 278]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=585099 KU514_RS12755 WP_000688498.1 2562008..2562724(-) (agrA) [Staphylococcus aureus strain 278]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996