Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MYL46_RS02395 Genome accession   NZ_CP095801
Coordinates   489093..490217 (+) Length   374 a.a.
NCBI ID   WP_000228527.1    Uniprot ID   -
Organism   Escherichia coli strain E166     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 484093..495217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL46_RS02370 (MYL46_02355) mscL 484219..484629 (-) 411 WP_000022444.1 large-conductance mechanosensitive channel protein MscL -
  MYL46_RS02375 (MYL46_02360) trkA 484759..486135 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  MYL46_RS02380 (MYL46_02365) rsmB 486157..487446 (-) 1290 WP_001318069.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MYL46_RS02385 (MYL46_02370) fmt 487492..488439 (-) 948 WP_000004420.1 methionyl-tRNA formyltransferase -
  MYL46_RS02390 (MYL46_02375) def 488454..488963 (-) 510 WP_000114986.1 peptide deformylase -
  MYL46_RS02395 (MYL46_02380) dprA 489093..490217 (+) 1125 WP_000228527.1 DNA-protecting protein DprA Machinery gene
  MYL46_RS02400 (MYL46_02385) smg 490189..490662 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  MYL46_RS02405 (MYL46_02390) yrdD 490691..491233 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  MYL46_RS02410 (MYL46_02395) tsaC 491238..491810 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  MYL46_RS02415 (MYL46_02400) aroE 491815..492633 (+) 819 WP_000451227.1 shikimate dehydrogenase -
  MYL46_RS02420 (MYL46_02405) yrdB 492630..492887 (+) 258 WP_001070566.1 DUF1488 domain-containing protein -
  MYL46_RS02425 (MYL46_02410) yrdA 492863..493417 (-) 555 WP_001318068.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40982.87 Da        Isoelectric Point: 6.2662

>NTDB_id=584680 MYL46_RS02395 WP_000228527.1 489093..490217(+) (dprA) [Escherichia coli strain E166]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLSDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=584680 MYL46_RS02395 WP_000228527.1 489093..490217(+) (dprA) [Escherichia coli strain E166]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGTGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCTCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGTCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

43.658

90.642

0.396
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396