Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MW395_RS23375 Genome accession   NZ_CP095526
Coordinates   4636147..4637271 (+) Length   374 a.a.
NCBI ID   WP_000228540.1    Uniprot ID   -
Organism   Escherichia coli strain GN05505     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4631147..4642271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW395_RS23350 (MW395_23345) mscL 4631273..4631683 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  MW395_RS23355 (MW395_23350) trkA 4631813..4633189 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  MW395_RS23360 (MW395_23355) rsmB 4633211..4634500 (-) 1290 WP_001309796.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MW395_RS23365 (MW395_23360) fmt 4634546..4635493 (-) 948 WP_000004443.1 methionyl-tRNA formyltransferase -
  MW395_RS23370 (MW395_23365) def 4635508..4636017 (-) 510 WP_000114984.1 peptide deformylase -
  MW395_RS23375 (MW395_23370) dprA 4636147..4637271 (+) 1125 WP_000228540.1 DNA-protecting protein DprA Machinery gene
  MW395_RS23380 (MW395_23375) smg 4637243..4637716 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  MW395_RS23385 (MW395_23380) yrdD 4637745..4638287 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  MW395_RS23390 (MW395_23385) tsaC 4638292..4638864 (+) 573 WP_001310090.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  MW395_RS23395 (MW395_23390) aroE 4638869..4639687 (+) 819 WP_000451230.1 shikimate dehydrogenase -
  MW395_RS23400 (MW395_23395) yrdB 4639684..4639941 (+) 258 WP_001070562.1 DUF1488 domain-containing protein -
  MW395_RS23405 (MW395_23400) yrdA 4639917..4640471 (-) 555 WP_001286217.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41035.00 Da        Isoelectric Point: 6.1815

>NTDB_id=583708 MW395_RS23375 WP_000228540.1 4636147..4637271(+) (dprA) [Escherichia coli strain GN05505]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSYIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=583708 MW395_RS23375 WP_000228540.1 4636147..4637271(+) (dprA) [Escherichia coli strain GN05505]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGTATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGACGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.62

90.107

0.393
  dprA Legionella pneumophila strain ERS1305867

44.073

87.968

0.388