Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MW398_RS11770 Genome accession   NZ_CP095505
Coordinates   2177421..2178545 (-) Length   374 a.a.
NCBI ID   WP_000228517.1    Uniprot ID   A0A0H3EME5
Organism   Escherichia coli strain GN02050     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2172421..2183545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW398_RS11740 (MW398_11730) yrdA 2174221..2174775 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  MW398_RS11745 (MW398_11735) yrdB 2174751..2175008 (-) 258 WP_001070567.1 DUF1488 domain-containing protein -
  MW398_RS11750 (MW398_11740) aroE 2175005..2175823 (-) 819 WP_000451230.1 shikimate dehydrogenase -
  MW398_RS11755 (MW398_11745) tsaC 2175828..2176400 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  MW398_RS11760 (MW398_11750) yrdD 2176405..2176947 (-) 543 WP_001312137.1 type I DNA topoisomerase -
  MW398_RS11765 (MW398_11755) smg 2176976..2177449 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  MW398_RS11770 (MW398_11760) dprA 2177421..2178545 (-) 1125 WP_000228517.1 DNA-protecting protein DprA Machinery gene
  MW398_RS11775 (MW398_11765) def 2178675..2179184 (+) 510 WP_000114984.1 peptide deformylase -
  MW398_RS11780 (MW398_11770) fmt 2179199..2180146 (+) 948 WP_000004421.1 methionyl-tRNA formyltransferase -
  MW398_RS11785 (MW398_11775) rsmB 2180198..2181487 (+) 1290 WP_000744766.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MW398_RS11790 (MW398_11780) trkA 2181509..2182885 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  MW398_RS11795 (MW398_11785) mscL 2183015..2183428 (+) 414 WP_000022450.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40910.86 Da        Isoelectric Point: 6.0395

>NTDB_id=583241 MW398_RS11770 WP_000228517.1 2177421..2178545(-) (dprA) [Escherichia coli strain GN02050]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=583241 MW398_RS11770 WP_000228517.1 2177421..2178545(-) (dprA) [Escherichia coli strain GN02050]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3EME5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.355

82.888

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39