Detailed information NTG0582811

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KTR68_RS13670
• Genome accession: NZ_CP077757
• Coordinates: 2781602..2782645 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain WHC07
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2776602..2787645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTR68_RS13640	-	2777147..2777257 (+)	111	WP_031775032.1	hypothetical protein	-
KTR68_RS13645	-	2777286..2777699 (+)	414	WP_001670387.1	hypothetical protein	-
KTR68_RS13650	-	2778130..2779116 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
KTR68_RS13655	map	2779528..2780286 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KTR68_RS13660	-	2780503..2780889 (+)	387	WP_001110179.1	hypothetical protein	-
KTR68_RS13665	liaF	2780904..2781605 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KTR68_RS13670	vraS	2781602..2782645 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KTR68_RS13675	vraR	2782635..2783264 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KTR68_RS13680	-	2783376..2784593 (-)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
KTR68_RS13685	-	2784871..2785146 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
KTR68_RS13690	-	2785153..2785617 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KTR68_RS13695	-	2785764..2785964 (+)	201	WP_000180460.1	DUF1128 family protein	-
KTR68_RS13700	-	2785967..2787223 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=582811 KTR68_RS13670 WP_001017131.1 2781602..2782645(+) (vraS) [Staphylococcus aureus strain WHC07]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=582811 KTR68_RS13670 WP_001017131.1 2781602..2782645(+) (vraS) [Staphylococcus aureus strain WHC07]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1