Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   JGX27_RS02575 Genome accession   NZ_CP077423
Coordinates   471603..473480 (+) Length   625 a.a.
NCBI ID   WP_009853568.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus TX20005     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 466603..478480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGX27_RS02560 (JGX27_02560) fmt 468581..469516 (+) 936 WP_043878634.1 methionyl-tRNA formyltransferase -
  JGX27_RS02565 (JGX27_02565) rsmB 469506..470828 (+) 1323 WP_009853566.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  JGX27_RS02570 (JGX27_02570) - 470866..471603 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  JGX27_RS02575 (JGX27_02575) pknB 471603..473480 (+) 1878 WP_009853568.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  JGX27_RS02580 (JGX27_02580) liaF 473591..474286 (+) 696 WP_009853569.1 cell wall-active antibiotics response protein LiaF -
  JGX27_RS02585 (JGX27_02585) - 474283..475308 (+) 1026 WP_009853570.1 sensor histidine kinase -
  JGX27_RS02590 (JGX27_02590) - 475292..475936 (+) 645 WP_009853571.1 response regulator transcription factor -
  JGX27_RS02595 (JGX27_02595) - 476055..477455 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  JGX27_RS02600 (JGX27_02600) - 477455..477811 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67643.81 Da        Isoelectric Point: 5.0111

>NTDB_id=581496 JGX27_RS02575 WP_009853568.1 471603..473480(+) (pknB) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KAATENKATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNDYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVAAESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATVTAQTPYYGDTLSGNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=581496 JGX27_RS02575 WP_009853568.1 471603..473480(+) (pknB) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGACGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGCAGCAACAGAAAACAAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACTGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTTAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATGATTATGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATTAGTCAAACGCCTAGCGAAGGTGAAACCTTTAAGGTAAGTGGCGATGATAAGATTACCTTTAAAGTAGCCGC
AGAAAGCACAGTAACAATGCCAAATCTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTGACGGCTCTAGGTGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCATATTATGGTGATACACTAAGTGGTAACGTGGTACTTTATCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAG
ATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-575)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.143

93.92

0.64
  stkP/pknB Streptococcus salivarius strain HSISS4

64.856

94.24

0.611
  stkP Streptococcus pneumoniae TIGR4

54.795

93.44

0.512
  stkP Streptococcus pneumoniae D39

54.623

93.44

0.51
  stkP Streptococcus pneumoniae R6

54.623

93.44

0.51
  stkP Streptococcus pneumoniae Rx1

54.452

93.44

0.509