Detailed information NTG0058067

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SPN034156_RS13175
• Genome accession: NC_021006
• Coordinates: 1600813..1601400 (-)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae SPN034156
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1595813..1606400

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034156_RS08585 (SPN034156_15440)	-	1596274..1597614 (+)	1341	WP_000275284.1	sensor histidine kinase	-
SPN034156_RS08590 (SPN034156_15450)	blpC	1597659..1597814 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
SPN034156_RS08595 (SPN034156_15460)	-	1597871..1599232 (-)	1362	WP_001069095.1	bacteriocin secretion accessory protein	-
SPN034156_RS11655 (SPN034156_15470)	-	1599243..1600919 (-)	1677	Protein_1601	peptide cleavage/export ABC transporter	-
SPN034156_RS13175 (SPN034156_15480)	comA/nlmT	1600813..1601400 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
SPN034156_RS08615 (SPN034156_15490)	-	1601690..1601923 (+)	234	WP_001093273.1	hypothetical protein	-
SPN034156_RS08620 (SPN034156_15500)	-	1601955..1602644 (+)	690	WP_000760515.1	CPBP family intramembrane glutamic endopeptidase	-
SPN034156_RS08625 (SPN034156_15510)	blpZ	1602686..1602919 (+)	234	WP_000276498.1	immunity protein BlpZ	-
SPN034156_RS08630 (SPN034156_15520)	-	1603070..1603681 (+)	612	WP_000394028.1	type II CAAX endopeptidase family protein	-
SPN034156_RS08635 (SPN034156_15530)	-	1603843..1604637 (+)	795	WP_000363002.1	phosphotransferase family protein	-
SPN034156_RS08640 (SPN034156_15540)	trmB	1604634..1605269 (+)	636	WP_001266078.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
SPN034156_RS08645 (SPN034156_15550)	rimP	1605395..1605874 (+)	480	WP_001808916.1	ribosome maturation factor RimP	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=58067 SPN034156_RS13175 WP_000205166.1 1600813..1601400(-) (comA/nlmT) [Streptococcus pneumoniae SPN034156]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=58067 SPN034156_RS13175 WP_000205166.1 1600813..1601400(-) (comA/nlmT) [Streptococcus pneumoniae SPN034156]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497