Detailed information NTG0058064

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SPN034156_RS10550
• Genome accession: NC_021006
• Coordinates: 1970004..1972244 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942395.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN034156
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1965004..1977244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034156_RS10510 (SPN034156_18940)	-	1965154..1966122 (+)	969	WP_000658183.1	PhoH family protein	-
SPN034156_RS10515 (SPN034156_18950)	-	1966315..1966815 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
SPN034156_RS10520 (SPN034156_18960)	-	1966818..1967144 (+)	327	Protein_1962	TfoX/Sxy family protein	-
SPN034156_RS12955 (SPN034156_18970)	ald	1967445..1968556 (-)	1112	Protein_1963	alanine dehydrogenase	-
SPN034156_RS10540 (SPN034156_18980)	-	1968733..1969302 (+)	570	WP_000443747.1	GNAT family N-acetyltransferase	-
SPN034156_RS10545 (SPN034156_18990)	comEA/celA/cilE	1969370..1970020 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
SPN034156_RS10550 (SPN034156_19000)	comEC/celB	1970004..1972244 (+)	2241	WP_000942395.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SPN034156_RS10555	-	1972423..1972611 (+)	189	WP_001809102.1	hypothetical protein	-
SPN034156_RS10560 (SPN034156_19010)	-	1972643..1973230 (+)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
SPN034156_RS10565 (SPN034156_19020)	-	1973234..1974415 (+)	1182	WP_000655956.1	hypothetical protein	-
SPN034156_RS10570 (SPN034156_19030)	infC	1974722..1975252 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
SPN034156_RS10575 (SPN034156_19040)	rpmI	1975285..1975485 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
SPN034156_RS10580 (SPN034156_19050)	rplT	1975537..1975896 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
SPN034156_RS10585 (SPN034156_19060)	-	1975954..1976334 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84600.12 Da
• Isoelectric Point: 9.3408

>NTDB_id=58064 SPN034156_RS10550 WP_000942395.1 1970004..1972244(+) (comEC/celB) [Streptococcus pneumoniae SPN034156]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPREIGYGGHEDSLVLYGKL
LNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=58064 SPN034156_RS10550 WP_000942395.1 1970004..1972244(+) (comEC/celB) [Streptococcus pneumoniae SPN034156]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCAATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGTTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACTAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGTGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGTACTTGCCCATTTTCG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGGAAATTGGATATGGAGGTCATGAAGATTCCCTGGTTCTTTATGGGAAACTC
TTGAATAATCACTTTCTCTTCATAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGTATTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-632)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae D39	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae R6	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae Rx1	96.247	100	0.962
comEC/celB	Streptococcus mitis NCTC 12261	91.544	99.866	0.914
comEC/celB	Streptococcus mitis SK321	91.287	100	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	43.86	99.33	0.436