Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STO1_RS03470 Genome accession   NZ_AP018338
Coordinates   688499..689239 (+) Length   246 a.a.
NCBI ID   WP_084881745.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 683499..694239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS03460 (STO1_006770) - 684326..686851 (+) 2526 WP_096421983.1 MBL fold metallo-hydrolase -
  STO1_RS03465 (STO1_006780) - 686898..688376 (-) 1479 WP_000789711.1 oligosaccharide flippase family protein -
  STO1_RS03470 (STO1_006790) mecA 688499..689239 (+) 741 WP_084881745.1 adaptor protein MecA Regulator
  STO1_RS03475 (STO1_006800) - 689387..690673 (+) 1287 WP_096421985.1 homoserine dehydrogenase -
  STO1_RS03480 (STO1_006810) thrB 690675..691544 (+) 870 WP_096421987.1 homoserine kinase -
  STO1_RS03485 (STO1_006820) msrB 691644..692582 (+) 939 WP_070534598.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28566.40 Da        Isoelectric Point: 4.1134

>NTDB_id=58064 STO1_RS03470 WP_084881745.1 688499..689239(+) (mecA) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIAEKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFV
NLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=58064 STO1_RS03470 WP_084881745.1 688499..689239(+) (mecA) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAGATGAAACAAATCAGTGATACAACACTAAAAATCACGATGACTTTAGATGATTTGATGGACCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTAAGTTTCCGTGTGACACCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATCTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGAGAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATCTACTATATCCTGCGTTTCGTA
AATCTTGCTGACCTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACCTCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAAT
TTGCAGATGATAGTGACATCAGTCGTTCAGTTTTGCAGGAGTATGGGCAAATCTTGATTAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.164

99.187

0.894
  mecA Streptococcus pneumoniae D39

90.164

99.187

0.894
  mecA Streptococcus pneumoniae R6

90.164

99.187

0.894
  mecA Streptococcus pneumoniae TIGR4

89.754

99.187

0.89
  mecA Streptococcus mutans UA159

49.18

99.187

0.488
  mecA Streptococcus thermophilus LMD-9

46.825

100

0.48
  mecA Streptococcus thermophilus LMG 18311

46.429

100

0.476

Multiple sequence alignment